4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations
OBJECTIVES/GOALS: Several lines of studies have supported the existence of periodontitis (inflammation of the gums) as a risk factor for cardiovascular disease (CVD). The goal of this study is to evaluate the relationship between periodontitis and CVD among Hispanic, African American, and Caucasian...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2020-06-01
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| Series: | Journal of Clinical and Translational Science |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2059866120004227/type/journal_article |
| _version_ | 1811155144230830080 |
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| author | Magda Shaheen Neeraj Harish Khona Katrina Schrode |
| author_facet | Magda Shaheen Neeraj Harish Khona Katrina Schrode |
| author_sort | Magda Shaheen |
| collection | DOAJ |
| description | OBJECTIVES/GOALS: Several lines of studies have supported the existence of periodontitis (inflammation of the gums) as a risk factor for cardiovascular disease (CVD). The goal of this study is to evaluate the relationship between periodontitis and CVD among Hispanic, African American, and Caucasian populations. METHODS/STUDY POPULATION: We analyzed data from the National Health and Nutrition Examination Survey, 1999-2004 (NHANES). The population was all adults with a periodontal exam. Periodontal Disease was defined as mild, moderate, and severe (2 loss of attachments of at least 3mm, 2 sites with probing depth of at least 4mm, or one site with probing depth of at least 5mm). Cardiovascular disease was defined by a questionnaire regarding prevalence of any of 5 diagnosis (congestive heart failure [CHF], coronary artery disease [CAD], angina, heart attack or stroke). Data were analyzed using multinomial regression in SAS version 9.3 taking into consideration the design and weight. RESULTS/ANTICIPATED RESULTS: The study included 3375 adults; 13% were Hispanic and 10% were Blacks, 58% had > high school education, 81% were insured, 11% were heavy alcohol drinkers, 27% were smokers, 13% were physically inactive, 14% had periodontitis, 62% visited dentist last year, 2% had CHD, and 1.5% had CHF or stroke. In the multiple multinomial regression, overall, people with periodontitis were more likely to have both CHD (AOR = 2.0, 95% CI = 1.1-3.8, p<0.05) and CHF or stroke (AOR = 1.8, 95% CI = 1.01, 3.0, p<0.05) than to have no heart condition. There was a racial/ethnic difference in the relationship between periodontitis and cardiovascular disease but it was not statistically significant (p>0.05). DISCUSSION/SIGNIFICANCE OF IMPACT: Overall, people with periodontitis were more likely to have CHD, CHF or stroke than to have no heart condition, but with no significant effect of racial/ethnic group. This study provides a foundation to future studies on the connection of periodontitis and CVD in relation to ethnic/racial groups. |
| first_indexed | 2024-04-10T04:28:10Z |
| format | Article |
| id | doaj.art-20f2f226ae8b4a84af86b22db076608b |
| institution | Directory Open Access Journal |
| issn | 2059-8661 |
| language | English |
| last_indexed | 2024-04-10T04:28:10Z |
| publishDate | 2020-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Journal of Clinical and Translational Science |
| spelling | doaj.art-20f2f226ae8b4a84af86b22db076608b2023-03-10T08:51:34ZengCambridge University PressJournal of Clinical and Translational Science2059-86612020-06-01414314310.1017/cts.2020.4224239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populationsMagda Shaheen0Neeraj Harish Khona1Katrina Schrode2David Geffen School of Medicine at UCLACharles R Drew UniversityCharles R Drew UniversityOBJECTIVES/GOALS: Several lines of studies have supported the existence of periodontitis (inflammation of the gums) as a risk factor for cardiovascular disease (CVD). The goal of this study is to evaluate the relationship between periodontitis and CVD among Hispanic, African American, and Caucasian populations. METHODS/STUDY POPULATION: We analyzed data from the National Health and Nutrition Examination Survey, 1999-2004 (NHANES). The population was all adults with a periodontal exam. Periodontal Disease was defined as mild, moderate, and severe (2 loss of attachments of at least 3mm, 2 sites with probing depth of at least 4mm, or one site with probing depth of at least 5mm). Cardiovascular disease was defined by a questionnaire regarding prevalence of any of 5 diagnosis (congestive heart failure [CHF], coronary artery disease [CAD], angina, heart attack or stroke). Data were analyzed using multinomial regression in SAS version 9.3 taking into consideration the design and weight. RESULTS/ANTICIPATED RESULTS: The study included 3375 adults; 13% were Hispanic and 10% were Blacks, 58% had > high school education, 81% were insured, 11% were heavy alcohol drinkers, 27% were smokers, 13% were physically inactive, 14% had periodontitis, 62% visited dentist last year, 2% had CHD, and 1.5% had CHF or stroke. In the multiple multinomial regression, overall, people with periodontitis were more likely to have both CHD (AOR = 2.0, 95% CI = 1.1-3.8, p<0.05) and CHF or stroke (AOR = 1.8, 95% CI = 1.01, 3.0, p<0.05) than to have no heart condition. There was a racial/ethnic difference in the relationship between periodontitis and cardiovascular disease but it was not statistically significant (p>0.05). DISCUSSION/SIGNIFICANCE OF IMPACT: Overall, people with periodontitis were more likely to have CHD, CHF or stroke than to have no heart condition, but with no significant effect of racial/ethnic group. This study provides a foundation to future studies on the connection of periodontitis and CVD in relation to ethnic/racial groups.https://www.cambridge.org/core/product/identifier/S2059866120004227/type/journal_article |
| spellingShingle | Magda Shaheen Neeraj Harish Khona Katrina Schrode 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations Journal of Clinical and Translational Science |
| title | 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| title_full | 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| title_fullStr | 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| title_full_unstemmed | 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| title_short | 4239 Racial/ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| title_sort | 4239 racial ethnic difference in the relationship between periodontitis and cardiovascular disease among adult populations |
| url | https://www.cambridge.org/core/product/identifier/S2059866120004227/type/journal_article |
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