Tracers for non-invasive radionuclide imaging of immune checkpoint expression in cancer

Tracers for non-invasive radionuclide imaging of immune checkpoint expression in cancer

Abstract Immunotherapy with checkpoint inhibitors demonstrates impressive improvements in the treatment of several types of cancer. Unfortunately, not all patients respond to therapy while severe immune-related adverse effects are prevalent. Currently, patient stratification is based on immunotherap...

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Bibliographic Details
Main Authors: Peter Wierstra, Gerwin Sandker, Erik Aarntzen, Martin Gotthardt, Gosse Adema, Johan Bussink, René Raavé, Sandra Heskamp
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Immune checkpoint
Immune checkpoint imaging
Tumor expression
PET
SPECT
PD-1
Online Access:http://link.springer.com/article/10.1186/s41181-019-0078-z

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