Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration

Looking downstream: the role of cyclic AMP-regulated genes in axonal regeneration

Elevation of intracellular cyclic AMP (cAMP) levels has proven to be one of the most effective means of overcoming inhibition of axonal regeneration by myelin-associated inhibitors such as myelin-associated glycoprotein, Nogo, and oligodendrocyte myelin glycoprotein. Pharmacological manipulation of...

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Bibliographic Details
Main Authors: Mustafa M Siddiq, Sari S Hannila
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Cyclic AMP
Interleukin-6
Metallothionein
Regeneration
gene
CREB
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00026/full

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