Phenotypic Heterogeneity of Cancer Associated Fibroblasts in Cervical Cancer Progression: FAP as a Central Activation Marker

Phenotypic Heterogeneity of Cancer Associated Fibroblasts in Cervical Cancer Progression: FAP as a Central Activation Marker

Cervical cancer (CC) is the fourth leading cancer among women and is one of the principal gynecological malignancies. In the tumor microenvironment, cancer-associated fibroblasts (CAFs) play a crucial role during malignant progression, exhibiting a variety of heterogeneous phenotypes. CAFs express p...

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Bibliographic Details
Main Authors: Lesly Jazmin Bueno-Urquiza, Marisol Godínez-Rubí, Julio César Villegas-Pineda, Alejandra Natali Vega-Magaña, Luis Felipe Jave-Suárez, Ana Graciela Puebla-Mora, Gloria Estefanía Aguirre-Sandoval, María Guadalupe Martínez-Silva, Adrián Ramírez-de-Arellano, Ana Laura Pereira-Suárez
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
cancer-associated fibroblasts
fibroblast activation protein
cervical cancer
mesenquimal stem cells
heterogeneous phenotypes
Online Access:https://www.mdpi.com/2073-4409/13/7/560

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