Curcumin analog WZ26 induces ROS and cell death via inhibition of STAT3 in cholangiocarcinoma

Curcumin analog WZ26 induces ROS and cell death via inhibition of STAT3 in cholangiocarcinoma

Cholangiocarcinoma (CCA) is an aggressive biliary epithelial tumor with limited therapeutic options and poor prognosis. Curcumin is a promising active natural compound with several anti-cancer properties, though its clinical uses remain hindered due to its poor bioavailability. We recently synthesiz...

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Bibliographic Details
Main Authors: Minxiao Chen, Chenchen Qian, Bo Jin, Chenghong Hu, Lingxi Zhang, Minshan Wang, Bin Zhou, Wei Zuo, Lijiang Huang, Yi Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Cancer Biology & Therapy
Subjects:
curcumin analog
mitochondrial apoptosis
cholangiocarcinoma
ros
stat3
Online Access:http://dx.doi.org/10.1080/15384047.2022.2162807

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