A protocol for a trial of homeopathic treatment for irritable bowel syndrome
<p>Abstract</p> <p>Background</p> <p>Irritable bowel syndrome is a chronic condition with no known cure. Many sufferers seek complementary and alternative medicine including homeopathic treatment. However there is much controversy as to the effectiveness of homeopathic...
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| Format: | Article |
| Language: | English |
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BMC
2012-11-01
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| Series: | BMC Complementary and Alternative Medicine |
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| Online Access: | http://www.biomedcentral.com/1472-6882/12/212 |
| _version_ | 1811265726460198912 |
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| author | Peckham Emily J Relton Clare Raw Jackie Walters Clare Thomas Kate Smith Christine |
| author_facet | Peckham Emily J Relton Clare Raw Jackie Walters Clare Thomas Kate Smith Christine |
| author_sort | Peckham Emily J |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Irritable bowel syndrome is a chronic condition with no known cure. Many sufferers seek complementary and alternative medicine including homeopathic treatment. However there is much controversy as to the effectiveness of homeopathic treatment. This three-armed study seeks to explore the effectiveness of individualised homeopathic treatment plus usual care compared to both an attention control plus usual care and usual care alone, for patients with irritable bowel syndrome.</p> <p>Methods/design</p> <p>This is a three-armed pragmatic randomised controlled trial using the cohort multiple randomised trial methodology. Patients are recruited to an irritable bowel syndrome cohort from primary and secondary care using GP databases and consultants lists respectively. From this cohort patients are randomly selected to be offered, 5 sessions of homeopathic treatment plus usual care, 5 sessions of supportive listening plus usual care or usual care alone. The primary clinical outcome is the Irritable Bowel Syndrome Symptom Severity at 26 weeks.</p> <p>From a power calculation, it is estimated that 33 people will be needed for the homeopathic treatment arm and 132 for the usual care arm, to detect a minimal clinical difference at 80 percent power and 5 percent significance allowing for loss to follow up. An unequal group size has been used for reasons of cost. Analysis will be by intention to treat and will compare homeopathic treatment with usual care at 26 weeks as the primary analysis, and homeopathic treatment with supportive listening as an additional analysis.</p> <p>Discussion</p> <p>This trial has received NHS approval and results are expected in 2013.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN90651143</p> |
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| institution | Directory Open Access Journal |
| issn | 1472-6882 |
| language | English |
| last_indexed | 2024-04-12T20:29:03Z |
| publishDate | 2012-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary and Alternative Medicine |
| spelling | doaj.art-20f55340aa1e4b7ea3d02ad6d83f949c2022-12-22T03:17:47ZengBMCBMC Complementary and Alternative Medicine1472-68822012-11-0112121210.1186/1472-6882-12-212A protocol for a trial of homeopathic treatment for irritable bowel syndromePeckham Emily JRelton ClareRaw JackieWalters ClareThomas KateSmith Christine<p>Abstract</p> <p>Background</p> <p>Irritable bowel syndrome is a chronic condition with no known cure. Many sufferers seek complementary and alternative medicine including homeopathic treatment. However there is much controversy as to the effectiveness of homeopathic treatment. This three-armed study seeks to explore the effectiveness of individualised homeopathic treatment plus usual care compared to both an attention control plus usual care and usual care alone, for patients with irritable bowel syndrome.</p> <p>Methods/design</p> <p>This is a three-armed pragmatic randomised controlled trial using the cohort multiple randomised trial methodology. Patients are recruited to an irritable bowel syndrome cohort from primary and secondary care using GP databases and consultants lists respectively. From this cohort patients are randomly selected to be offered, 5 sessions of homeopathic treatment plus usual care, 5 sessions of supportive listening plus usual care or usual care alone. The primary clinical outcome is the Irritable Bowel Syndrome Symptom Severity at 26 weeks.</p> <p>From a power calculation, it is estimated that 33 people will be needed for the homeopathic treatment arm and 132 for the usual care arm, to detect a minimal clinical difference at 80 percent power and 5 percent significance allowing for loss to follow up. An unequal group size has been used for reasons of cost. Analysis will be by intention to treat and will compare homeopathic treatment with usual care at 26 weeks as the primary analysis, and homeopathic treatment with supportive listening as an additional analysis.</p> <p>Discussion</p> <p>This trial has received NHS approval and results are expected in 2013.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN90651143</p>http://www.biomedcentral.com/1472-6882/12/212Irritable bowel syndromeHomeopathic treatmentAttention controlRandomised controlled trial |
| spellingShingle | Peckham Emily J Relton Clare Raw Jackie Walters Clare Thomas Kate Smith Christine A protocol for a trial of homeopathic treatment for irritable bowel syndrome BMC Complementary and Alternative Medicine Irritable bowel syndrome Homeopathic treatment Attention control Randomised controlled trial |
| title | A protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| title_full | A protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| title_fullStr | A protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| title_full_unstemmed | A protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| title_short | A protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| title_sort | protocol for a trial of homeopathic treatment for irritable bowel syndrome |
| topic | Irritable bowel syndrome Homeopathic treatment Attention control Randomised controlled trial |
| url | http://www.biomedcentral.com/1472-6882/12/212 |
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