Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization

Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization

Chronic kidney disease (CKD) is represented by a diminished filtration capacity of the kidneys. End-stage renal disease patients need dialysis treatment to remove waste and toxins from the circulation. However, endogenously produced uremic toxins (UTs) cannot always be filtered during dialysis. UTs...

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Bibliographic Details
Main Authors: Willem B. van Ham, Carlijn M. Cornelissen, Elizaveta Polyakova, Stephanie M. van der Voorn, Merel L. Ligtermoet, Jantine Monshouwer-Kloots, Marc A. Vos, Alexandre Bossu, Eva van Rooij, Marcel A. G. van der Heyden, Toon A. B. van Veen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
cellular electrophysiology
uremic toxins
chronic kidney disease
K<sub>V</sub>11.1
cardiac repolarization
Online Access:https://www.mdpi.com/1422-0067/24/6/5373

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https://www.mdpi.com/1422-0067/24/6/5373

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