Identification of a new human mtDNA polymorphism (A14290G) in the NADH dehydrogenase subunit 6 gene

Identification of a new human mtDNA polymorphism (A14290G) in the NADH dehydrogenase subunit 6 gene

Leber's hereditary optic neuropathy (LHON) is a maternally inherited form of retinal ganglion cell degeneration leading to optic atrophy in young adults. Several mutations in different genes can cause LHON (heterogeneity). The ND6 gene is one of the mitochondrial genes that encodes subunit 6 of...

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Bibliographic Details
Main Authors: M. Houshmand, T. Mahmoudi, M. Shafa Shariat Panahi, Y. Seyedena, S. Saber, M. Ataei
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Leber's hereditary optic neuropathy
ND6 gene
Mitochondrial DNA mutations
Single-strand conformational polymorphism
mtDNA A14290G allele
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600004

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600004

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