Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People
Fecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with <i>C. cayetanensis</i> in Colombi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/9/3/627 |
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| author | Hagen Frickmann Juliane Alker Jessica Hansen Juan Carlos Dib Andrés Aristizabal Gustavo Concha Ulrich Schotte Simone Kann |
| author_facet | Hagen Frickmann Juliane Alker Jessica Hansen Juan Carlos Dib Andrés Aristizabal Gustavo Concha Ulrich Schotte Simone Kann |
| author_sort | Hagen Frickmann |
| collection | DOAJ |
| description | Fecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with <i>C. cayetanensis</i> in Colombian indigenous people living under very restricted conditions. In the rainy season between July and November and in the dry season between January and April, stool samples from indigenous people with and without gastrointestinal symptoms were collected and screened for <i>C. cayetanensis</i> applying in-house real-time polymerase chain reaction (PCR). In the rainy season and in the dry season, positive PCR results were observed for 11.8% (16/136) and 5.1% (15/292), respectively, with cycle threshold (Ct) values of 30.6 (±3.4) and 34.4 (±1.6), respectively. Despite higher parasite loads in the rainy season, fewer individuals (2/16, 12.5%) reported gastrointestinal symptoms compared to the dry season (6/15, 40%). In conclusion, considerable prevalence of <i>C. cayetanensis</i> in Colombian indigenous people persists in the dry season. Low proportions of gastrointestinal symptoms along with higher parasite loads make colonization likely rather than infection. |
| first_indexed | 2024-03-10T13:08:27Z |
| format | Article |
| id | doaj.art-2100be94532f4adeaa761adcf09380df |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T13:08:27Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-2100be94532f4adeaa761adcf09380df2023-11-21T10:56:53ZengMDPI AGMicroorganisms2076-26072021-03-019362710.3390/microorganisms9030627Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous PeopleHagen Frickmann0Juliane Alker1Jessica Hansen2Juan Carlos Dib3Andrés Aristizabal4Gustavo Concha5Ulrich Schotte6Simone Kann7Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, 20359 Hamburg, GermanyCentral Institute of the Bundeswehr Medical Service Kiel, Department A—Veterinary Medicine, 24119 Kronshagen, GermanyDepartment for Infectious Disease Diagnostics, Bernhard-Nocht Institute for Tropical Medicine, 20359 Hamburg, GermanyTropical Health Foundation, Santa Marta 470003, ColombiaTropical Health Foundation, Santa Marta 470003, ColombiaOrganization Wiwa Yugumaiun Bunkauanarrua Tayrona (OWYBT), Department Health Advocacy, Valledupar 200001, ColombiaCentral Institute of the Bundeswehr Medical Service Kiel, Department A—Veterinary Medicine, 24119 Kronshagen, GermanyMedical Mission Institute, 97074 Würzburg, GermanyFecal-orally transmitted cyclosporiasis is frequent in remote resource-limited settings in Central and South America with poor hygiene conditions. In this study, we aimed at assessing seasonal effects on the epidemiology of colonization or infection with <i>C. cayetanensis</i> in Colombian indigenous people living under very restricted conditions. In the rainy season between July and November and in the dry season between January and April, stool samples from indigenous people with and without gastrointestinal symptoms were collected and screened for <i>C. cayetanensis</i> applying in-house real-time polymerase chain reaction (PCR). In the rainy season and in the dry season, positive PCR results were observed for 11.8% (16/136) and 5.1% (15/292), respectively, with cycle threshold (Ct) values of 30.6 (±3.4) and 34.4 (±1.6), respectively. Despite higher parasite loads in the rainy season, fewer individuals (2/16, 12.5%) reported gastrointestinal symptoms compared to the dry season (6/15, 40%). In conclusion, considerable prevalence of <i>C. cayetanensis</i> in Colombian indigenous people persists in the dry season. Low proportions of gastrointestinal symptoms along with higher parasite loads make colonization likely rather than infection.https://www.mdpi.com/2076-2607/9/3/627<i>Cyclospora cayetanensis</i>Colombiaindigenous peopleprevalenceseasonalityinfection |
| spellingShingle | Hagen Frickmann Juliane Alker Jessica Hansen Juan Carlos Dib Andrés Aristizabal Gustavo Concha Ulrich Schotte Simone Kann Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People Microorganisms <i>Cyclospora cayetanensis</i> Colombia indigenous people prevalence seasonality infection |
| title | Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People |
| title_full | Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People |
| title_fullStr | Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People |
| title_full_unstemmed | Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People |
| title_short | Seasonal Differences in <i>Cyclospora cayetanensis</i> Prevalence in Colombian Indigenous People |
| title_sort | seasonal differences in i cyclospora cayetanensis i prevalence in colombian indigenous people |
| topic | <i>Cyclospora cayetanensis</i> Colombia indigenous people prevalence seasonality infection |
| url | https://www.mdpi.com/2076-2607/9/3/627 |
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