Domperidone inhibits cell proliferation via targeting MEK and CDK4 in esophageal squamous cell carcinoma

Domperidone inhibits cell proliferation via targeting MEK and CDK4 in esophageal squamous cell carcinoma

Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the leading causes of digestive system tumor related death in the world. Unfortunately, effective chemopreventive agent is lack for patients with ESCC in clinical practice, which leads to the extremely high mortality rate. Metho...

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Bibliographic Details
Main Authors: Qiang Yuan, Yunshu Shi, Yuhan Zhang, Yaqian Shi, Zubair Hussain, Jimin Zhao, Yanan jiang, Yan Qiao, Yaping Guo, Jing Lu, Ziming Dong, Zigang Dong, Junyong Wang, Kangdong Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cancer Cell International
Subjects:
MEK1/2
CDK4
Domperidone
ESCC
Online Access:https://doi.org/10.1186/s12935-024-03291-8

Internet

https://doi.org/10.1186/s12935-024-03291-8

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