Extracellular Vesicles-Loaded Fibrin Gel Supports Rapid Neovascularization for Dental Pulp Regeneration

Extracellular Vesicles-Loaded Fibrin Gel Supports Rapid Neovascularization for Dental Pulp Regeneration

Rapid vascularization is required for the regeneration of dental pulp due to the spatially restricted tooth environment. Extracellular vesicles (EVs) released from mesenchymal stromal cells show potent proangiogenic effects. Since EVs suffer from rapid clearance and low accumulation in target tissue...

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Bibliographic Details
Main Authors: Siyuan Zhang, Anja Lena Thiebes, Franziska Kreimendahl, Stephan Ruetten, Eva Miriam Buhl, Michael Wolf, Stefan Jockenhoevel, Christian Apel
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles (EVs)
dental pulp regeneration
hydrogel
angiogenesis
rapid vascularization
VEGF
Online Access:https://www.mdpi.com/1422-0067/21/12/4226

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