Role of proteoglycan synthesis genes in osteosarcoma stem cells

Role of proteoglycan synthesis genes in osteosarcoma stem cells

Osteosarcoma stem cells (OSCs) contribute to the pathogenesis of osteosarcoma (OS), which is the most common malignant primary bone tumor. The significance and underlying mechanisms of action of proteoglycans (PGs) and glycosaminoglycans (GAGs) in OSC phenotypes and OS malignancy are largely unknown...

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Bibliographic Details
Main Authors: Ryoma Osumi, Kengo Sugihara, Makoto Yoshimoto, Kazuya Tokumura, Yuki Tanaka, Eiichi Hinoi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Oncology
Subjects:
osteosarcoma
osteosarcoma stem cell
proteoglycan
glycosaminoglycan
β-1
3glucuronyltransferase 3
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1325794/full

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