Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves
Rourea coccinea is widely used as a medicinal plant in the world, especially in West Africa. The phytochemical screening of ethanolic extract of leaves by applying the Houghton and Raman method with some modifications revealed the presence of alkaloids, phenolic compounds, terpenoids, tannins, couma...
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University of Brawijaya
2023-08-01
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| Series: | Journal of Pure and Applied Chemistry Research |
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| Online Access: | https://jpacr.ub.ac.id/index.php/jpacr/article/view/3314/pdf |
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| author | Basile Goueti Bénédicta Kpadonou-Kpoviessi Raymond Fatondji Bardieu Atchade Paul Djouonzo Toukam Salomé Kpoviessi |
| author_facet | Basile Goueti Bénédicta Kpadonou-Kpoviessi Raymond Fatondji Bardieu Atchade Paul Djouonzo Toukam Salomé Kpoviessi |
| author_sort | Basile Goueti |
| collection | DOAJ |
| description | Rourea coccinea is widely used as a medicinal plant in the world, especially in West Africa. The phytochemical screening of ethanolic extract of leaves by applying the Houghton and Raman method with some modifications revealed the presence of alkaloids, phenolic compounds, terpenoids, tannins, coumarins, anthocyanins and anthraquinones. The antiradical test was performed using DPPH (2,2-diphenyl-1-picryhydrazyl), ABTS (2,2-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt) and FRAP (Ferric Reducing Antioxidant Power) with a Scavenging concentration 50 (SC50) of 101.19
µg/mL, 34.73 µg/mL and 88.93 µg/mL respectively. The extract anti-shigella activity determined by the microdilution method was low. According to Jair Siquera-Neto et al., the antileishmanial study using the colorimetric resealing method showed activity against promastigote strains of Leishmania donovani with an inhibitory concentration of IC50=32.26 µg/mL. The traditional use of Rourea coccinea, to treat several diseases, would be justified by these pharmacological property's tests. |
| first_indexed | 2024-03-11T15:06:35Z |
| format | Article |
| id | doaj.art-21096b39de6242eb8e85c7221b1abce6 |
| institution | Directory Open Access Journal |
| issn | 2302-4690 2541-0733 |
| language | English |
| last_indexed | 2024-03-11T15:06:35Z |
| publishDate | 2023-08-01 |
| publisher | University of Brawijaya |
| record_format | Article |
| series | Journal of Pure and Applied Chemistry Research |
| spelling | doaj.art-21096b39de6242eb8e85c7221b1abce62023-10-30T04:29:41ZengUniversity of BrawijayaJournal of Pure and Applied Chemistry Research2302-46902541-07332023-08-011225764Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth LeavesBasile Goueti0Bénédicta Kpadonou-Kpoviessi1Raymond Fatondji2Bardieu Atchade3Paul Djouonzo Toukam4Salomé Kpoviessi5Laboratory of Physic and Synthesis Organic Chemistry (LaCOPS), University of Abomey-Calavi (UAC), Faculty of Sciences and Technics (FAST), 01 BP : 4166 Cotonou, Benin; Laboratory of Pharmacognosy and Essential Oils (LAPHE), University of Abomey-Calavi (UAC), Faculty of Health Sciences (FSS), Faculty of Sciences and Technics (FAST), 01 BP: 188 Cotonou, Benin; Center for Studies on Medicinal Plants and Traditionnal Medicine (CRPMT) Institute of Medical Research and Medicinal plants Studies (IMPM), PO. Box 13033, yaoundé, CameroonLaboratory of Physic and Synthesis Organic Chemistry (LaCOPS), University of Abomey-Calavi (UAC), Faculty of Sciences and Technics (FAST), 01 BP : 4166 Cotonou, Benin; Laboratory of Pharmacognosy and Essential Oils (LAPHE), University of Abomey-Calavi (UAC), Faculty of Health Sciences (FSS), Faculty of Sciences and Technics (FAST), 01 BP: 188 Cotonou, BeninLaboratory of Physic and Synthesis Organic Chemistry (LaCOPS), University of Abomey-Calavi (UAC), Faculty of Sciences and Technics (FAST), 01 BP : 4166 Cotonou, BeninLaboratory of Physic and Synthesis Organic Chemistry (LaCOPS), University of Abomey-Calavi (UAC), Faculty of Sciences and Technics (FAST), 01 BP : 4166 Cotonou, BeninCenter for Studies on Medicinal Plants and Traditionnal Medicine (CRPMT) Institute of Medical Research and Medicinal plants Studies (IMPM), PO. Box 13033, yaoundé, CameroonLaboratory of Physic and Synthesis Organic Chemistry (LaCOPS), University of Abomey-Calavi (UAC), Faculty of Sciences and Technics (FAST), 01 BP : 4166 Cotonou, Benin; Laboratory of Pharmacognosy and Essential Oils (LAPHE), University of Abomey-Calavi (UAC), Faculty of Health Sciences (FSS), Faculty of Sciences and Technics (FAST), 01 BP: 188 Cotonou, BeninRourea coccinea is widely used as a medicinal plant in the world, especially in West Africa. The phytochemical screening of ethanolic extract of leaves by applying the Houghton and Raman method with some modifications revealed the presence of alkaloids, phenolic compounds, terpenoids, tannins, coumarins, anthocyanins and anthraquinones. The antiradical test was performed using DPPH (2,2-diphenyl-1-picryhydrazyl), ABTS (2,2-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt) and FRAP (Ferric Reducing Antioxidant Power) with a Scavenging concentration 50 (SC50) of 101.19 µg/mL, 34.73 µg/mL and 88.93 µg/mL respectively. The extract anti-shigella activity determined by the microdilution method was low. According to Jair Siquera-Neto et al., the antileishmanial study using the colorimetric resealing method showed activity against promastigote strains of Leishmania donovani with an inhibitory concentration of IC50=32.26 µg/mL. The traditional use of Rourea coccinea, to treat several diseases, would be justified by these pharmacological property's tests.https://jpacr.ub.ac.id/index.php/jpacr/article/view/3314/pdfrourea coccineamedicinal plantantioxidantantileishmanial and antishigella activity |
| spellingShingle | Basile Goueti Bénédicta Kpadonou-Kpoviessi Raymond Fatondji Bardieu Atchade Paul Djouonzo Toukam Salomé Kpoviessi Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves Journal of Pure and Applied Chemistry Research rourea coccinea medicinal plant antioxidant antileishmanial and antishigella activity |
| title | Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves |
| title_full | Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves |
| title_fullStr | Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves |
| title_full_unstemmed | Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves |
| title_short | Phytochemical Screening, Antioxidant, Antishigella and Antileishmanial Activities of Ethanolic Extract of Rourea coccinea (Schumach & Thonn.) Benth Leaves |
| title_sort | phytochemical screening antioxidant antishigella and antileishmanial activities of ethanolic extract of rourea coccinea schumach thonn benth leaves |
| topic | rourea coccinea medicinal plant antioxidant antileishmanial and antishigella activity |
| url | https://jpacr.ub.ac.id/index.php/jpacr/article/view/3314/pdf |
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