Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination
This is a case report of a Chinese adolescent boy who had multiple autoimmune syndrome (MAS) of a rare combination comprising type 1 diabetes, Hashimoto thyroiditis and childhood-onset systemic lupus erythematosus (SLE). He developed SLE within one year of symptom onset, presenting with necrotising...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.1054025/full |
| _version_ | 1797988536151965696 |
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| author | Elaine Yi Lee Kwong Manson Chon In Kuok Winnie Kwai-Yu Chan |
| author_facet | Elaine Yi Lee Kwong Manson Chon In Kuok Winnie Kwai-Yu Chan |
| author_sort | Elaine Yi Lee Kwong |
| collection | DOAJ |
| description | This is a case report of a Chinese adolescent boy who had multiple autoimmune syndrome (MAS) of a rare combination comprising type 1 diabetes, Hashimoto thyroiditis and childhood-onset systemic lupus erythematosus (SLE). He developed SLE within one year of symptom onset, presenting with necrotising histiocytic lymphadenitis and hepatitis. We highlight the importance for physicians to be aware of the need for continued surveillance for developing new autoimmune diseases in patients with multiple autoimmune diseases. It is also essential to remain vigilant for overlap syndrome as autoimmune diseases commonly share similar subphenotypes and non-specific autoantibodies. Long-term follow-up is warranted to define the final phenotype. |
| first_indexed | 2024-04-11T08:05:35Z |
| format | Article |
| id | doaj.art-211605a83253481fbbdeb120c65b15b6 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T08:05:35Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-211605a83253481fbbdeb120c65b15b62022-12-22T04:35:34ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-11-011010.3389/fped.2022.10540251054025Case Report: Multiple autoimmune syndrome (MAS)—An unusual combinationElaine Yi Lee KwongManson Chon In KuokWinnie Kwai-Yu ChanThis is a case report of a Chinese adolescent boy who had multiple autoimmune syndrome (MAS) of a rare combination comprising type 1 diabetes, Hashimoto thyroiditis and childhood-onset systemic lupus erythematosus (SLE). He developed SLE within one year of symptom onset, presenting with necrotising histiocytic lymphadenitis and hepatitis. We highlight the importance for physicians to be aware of the need for continued surveillance for developing new autoimmune diseases in patients with multiple autoimmune diseases. It is also essential to remain vigilant for overlap syndrome as autoimmune diseases commonly share similar subphenotypes and non-specific autoantibodies. Long-term follow-up is warranted to define the final phenotype.https://www.frontiersin.org/articles/10.3389/fped.2022.1054025/fullmultiple autoimmune syndrome (MAS)diabetes mellites (DM)autoimmune thyroid deseasesystemic lupus erythematosuskikuchi - fujimoto disease |
| spellingShingle | Elaine Yi Lee Kwong Manson Chon In Kuok Winnie Kwai-Yu Chan Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination Frontiers in Pediatrics multiple autoimmune syndrome (MAS) diabetes mellites (DM) autoimmune thyroid desease systemic lupus erythematosus kikuchi - fujimoto disease |
| title | Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination |
| title_full | Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination |
| title_fullStr | Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination |
| title_full_unstemmed | Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination |
| title_short | Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination |
| title_sort | case report multiple autoimmune syndrome mas an unusual combination |
| topic | multiple autoimmune syndrome (MAS) diabetes mellites (DM) autoimmune thyroid desease systemic lupus erythematosus kikuchi - fujimoto disease |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.1054025/full |
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