Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis
We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at t...
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Format: | Article |
Language: | English |
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Jin Publishing & Printing Co.
2018-02-01
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Series: | The Korean Journal of Gastroenterology |
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Online Access: | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.2.98 |
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author | Minjeong Kim Jin Myung Park Sung Joon Lee Chang Don Kang MyungHo Kang Ji Hyun Kim Seungkoo Lee Seong Whi Cho |
author_facet | Minjeong Kim Jin Myung Park Sung Joon Lee Chang Don Kang MyungHo Kang Ji Hyun Kim Seungkoo Lee Seong Whi Cho |
author_sort | Minjeong Kim |
collection | DOAJ |
description | We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at the pancreas body with a dilatation of the upstream pancreatic duct and mild infiltrations of peripancreatic fat. An endoscopic ultrasound-guided fine needle biopsy was performed for the pancreatic mass, but only necrotic tissue was observed on the pathologic examination. A chest and neck CT scan revealed anterior mediastinal, paratracheal, and cervical lymph node enlargement, which were indicative of metastasis. An ultrasound-guided core needle biopsy was performed for the enlarged neck lymph node, and pathologic examination revealed a metastatic poorly differentiated carcinoma. Immunohistochemical analysis showed positive staining for synaptophysin, chromogranin A, and CD 56, indicative of a neuroendocrine carcinoma. |
first_indexed | 2024-12-10T12:42:01Z |
format | Article |
id | doaj.art-2116cab747d14fab83e23bfaf038ecee |
institution | Directory Open Access Journal |
issn | 1598-9992 |
language | English |
last_indexed | 2024-12-10T12:42:01Z |
publishDate | 2018-02-01 |
publisher | Jin Publishing & Printing Co. |
record_format | Article |
series | The Korean Journal of Gastroenterology |
spelling | doaj.art-2116cab747d14fab83e23bfaf038ecee2022-12-22T01:48:30ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922018-02-017129810210.4166/kjg.2018.71.2.98kjg.2018.71.2.98Pancreatic Neuroendocrine Tumor Presenting as Acute PancreatitisMinjeong Kim0Jin Myung Park1Sung Joon Lee2Chang Don Kang3MyungHo Kang4Ji Hyun Kim5Seungkoo Lee6Seong Whi Cho7Departments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Anatomic Pathology, Kangwon National University School of Medicine, Chuncheon, KoreaDepartments of Radiology, Kangwon National University School of Medicine, Chuncheon, KoreaWe report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography revealed a 1.7 cm sized mass at the pancreas body with a dilatation of the upstream pancreatic duct and mild infiltrations of peripancreatic fat. An endoscopic ultrasound-guided fine needle biopsy was performed for the pancreatic mass, but only necrotic tissue was observed on the pathologic examination. A chest and neck CT scan revealed anterior mediastinal, paratracheal, and cervical lymph node enlargement, which were indicative of metastasis. An ultrasound-guided core needle biopsy was performed for the enlarged neck lymph node, and pathologic examination revealed a metastatic poorly differentiated carcinoma. Immunohistochemical analysis showed positive staining for synaptophysin, chromogranin A, and CD 56, indicative of a neuroendocrine carcinoma.http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.2.98Neuroendocrine tumorPancreatitisEndoscopic ultrasound-guided fine needle aspiration |
spellingShingle | Minjeong Kim Jin Myung Park Sung Joon Lee Chang Don Kang MyungHo Kang Ji Hyun Kim Seungkoo Lee Seong Whi Cho Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis The Korean Journal of Gastroenterology Neuroendocrine tumor Pancreatitis Endoscopic ultrasound-guided fine needle aspiration |
title | Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis |
title_full | Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis |
title_fullStr | Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis |
title_full_unstemmed | Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis |
title_short | Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis |
title_sort | pancreatic neuroendocrine tumor presenting as acute pancreatitis |
topic | Neuroendocrine tumor Pancreatitis Endoscopic ultrasound-guided fine needle aspiration |
url | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.2.98 |
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