BarWare: efficient software tools for barcoded single-cell genomics

BarWare: efficient software tools for barcoded single-cell genomics

Abstract Background Barcode-based multiplexing methods can be used to increase throughput and reduce batch effects in large single-cell genomics studies. Despite advantages in flexibility of sample collection and scale, there are additional complications in the data deconvolution steps required to a...

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Bibliographic Details
Main Authors: Elliott Swanson, Julian Reading, Lucas T. Graybuck, Peter J. Skene
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Bioinformatics
Subjects:
Single-cell RNA-seq
Cell hashing
Demultiplexing
Genomics
Online Access:https://doi.org/10.1186/s12859-022-04620-2

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