Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis
Th17 cells produce a range of characteristic Th17 type cytokines and express transcription factors governed by epigenetic regulation to engage the Th17 programme. Here the authors implicate the RNA 5- methylcytosine (m5C) methyltransferase Nsun2 in Th17 cells and the promotion of colitis in a murine...
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Bibliographic Details
Main Authors: |
Wen-Lan Yang,
Weinan Qiu,
Ting Zhang,
Kai Xu,
Zi-Juan Gu,
Yu Zhou,
Heng-Ji Xu,
Zhong-Zhou Yang,
Bin Shen,
Yong-Liang Zhao,
Qi Zhou,
Ying Yang,
Wei Li,
Peng-Yuan Yang,
Yun-Gui Yang |
Format: | Article
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Language: | English |
Published: |
Nature Portfolio
2023-02-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-023-36595-w
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