Impact of Gluten on Irritable Bowel Syndrome
Objective: To assess the impact of a gluten-free diet on the quality of life of patients managed for irritable bowel syndrome at a tertiary care hospital Study Design: Prospective comparative study. Place and Duration of Study: Department of Medicine/Gastroenterology, Pak Emirates Military Ho...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2023-08-01
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| Series: | Pakistan Armed Forces Medical Journal |
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| Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/6843 |
| _version_ | 1797690117966528512 |
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| author | Sana Uruj Muhammad Zafar Ali Natasha Sarwar Amina Hussain Muhammad Waseem |
| author_facet | Sana Uruj Muhammad Zafar Ali Natasha Sarwar Amina Hussain Muhammad Waseem |
| author_sort | Sana Uruj |
| collection | DOAJ |
| description |
Objective: To assess the impact of a gluten-free diet on the quality of life of patients managed for irritable bowel syndrome at a tertiary care hospital
Study Design: Prospective comparative study.
Place and Duration of Study: Department of Medicine/Gastroenterology, Pak Emirates Military Hospital, Rawalpindi Pakistan from Jul 2020 to May 2021.
Methodology: Two hundred patients with irritable bowel syndrome and diagnosed on the basis of Rome-IV criteria were included in this study. They were divided into two groups via a lottery method. Group-1 received treatment as usual, depending upon the type of irritable bowel syndrome. Group-2 received treatment as usual and a gluten-free diet. Quality of life was assessed after one month using the World Health Organization Quality of Life-Brief scale.
Results: Out of 200 patients with irritable bowel syndrome included in the study, 93(46.5%) were male, while 107(53.5%) were female. 125(62.5%) had good quality of life after one month of treatment, while 75(37.5%) had lesser quality of life. Statistical analysis revealed that irritable use of a gluten-free diet had a statistically significant relationship (p-value<0.001) with good quality of life after one month of treatment in study participants.
Conclusion: After one month of treatment, good quality of life was found in many patients with irritable bowel syndrome. The use of a gluten-free diet in addition to treatment, as usual, was associated with good quality of life than routine treatment in these patients.
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| first_indexed | 2024-03-12T01:54:59Z |
| format | Article |
| id | doaj.art-2117f2cf86c14a9baf1cdca40f6a78b6 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-03-12T01:54:59Z |
| publishDate | 2023-08-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-2117f2cf86c14a9baf1cdca40f6a78b62023-09-08T06:00:00ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-08-0173410.51253/pafmj.v73i4.6843Impact of Gluten on Irritable Bowel SyndromeSana Uruj0Muhammad Zafar Ali1Natasha Sarwar2Amina Hussain3Muhammad Waseem4Department of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanDepartment of Medicine, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To assess the impact of a gluten-free diet on the quality of life of patients managed for irritable bowel syndrome at a tertiary care hospital Study Design: Prospective comparative study. Place and Duration of Study: Department of Medicine/Gastroenterology, Pak Emirates Military Hospital, Rawalpindi Pakistan from Jul 2020 to May 2021. Methodology: Two hundred patients with irritable bowel syndrome and diagnosed on the basis of Rome-IV criteria were included in this study. They were divided into two groups via a lottery method. Group-1 received treatment as usual, depending upon the type of irritable bowel syndrome. Group-2 received treatment as usual and a gluten-free diet. Quality of life was assessed after one month using the World Health Organization Quality of Life-Brief scale. Results: Out of 200 patients with irritable bowel syndrome included in the study, 93(46.5%) were male, while 107(53.5%) were female. 125(62.5%) had good quality of life after one month of treatment, while 75(37.5%) had lesser quality of life. Statistical analysis revealed that irritable use of a gluten-free diet had a statistically significant relationship (p-value<0.001) with good quality of life after one month of treatment in study participants. Conclusion: After one month of treatment, good quality of life was found in many patients with irritable bowel syndrome. The use of a gluten-free diet in addition to treatment, as usual, was associated with good quality of life than routine treatment in these patients. https://www.pafmj.org/index.php/PAFMJ/article/view/6843GlutenIrritable bowel syndromeQuality of life |
| spellingShingle | Sana Uruj Muhammad Zafar Ali Natasha Sarwar Amina Hussain Muhammad Waseem Impact of Gluten on Irritable Bowel Syndrome Pakistan Armed Forces Medical Journal Gluten Irritable bowel syndrome Quality of life |
| title | Impact of Gluten on Irritable Bowel Syndrome |
| title_full | Impact of Gluten on Irritable Bowel Syndrome |
| title_fullStr | Impact of Gluten on Irritable Bowel Syndrome |
| title_full_unstemmed | Impact of Gluten on Irritable Bowel Syndrome |
| title_short | Impact of Gluten on Irritable Bowel Syndrome |
| title_sort | impact of gluten on irritable bowel syndrome |
| topic | Gluten Irritable bowel syndrome Quality of life |
| url | https://www.pafmj.org/index.php/PAFMJ/article/view/6843 |
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