Human bone marrow mesenchymal stem cells induce collagen production and tongue cancer invasion.

Human bone marrow mesenchymal stem cells induce collagen production and tongue cancer invasion.

Tumor microenvironment (TME) is an active player in carcinogenesis and changes in its composition modify cancer growth. Carcinoma-associated fibroblasts, bone marrow-derived multipotent mesenchymal stem cells (BMMSCs), and inflammatory cells can all affect the composition of TME leading to changes i...

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Bibliographic Details
Main Authors: Sirpa Salo, Carolina Bitu, Kalle Merkku, Pia Nyberg, Ibrahim O Bello, Jussi Vuoristo, Meeri Sutinen, Hannu Vähänikkilä, Daniela E Costea, Joonas H Kauppila, Petri Lehenkari, Dan Dayan, Marilena Vered, Juha Risteli, Tuula Salo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3804615?pdf=render

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