Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer

Background and objective To those patients with advanced lung cancer, the ultimate objective is to improve the curative effect and quality of life, lung function indexes are an important factor. We investigate the change of lung function and the relationship between pulmonary function indexs and sur...

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Main Authors: Hui GE, Zhenghua JIANG, Qian HUANG, Muyun ZHU, Jie YANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2013-07-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2013.07.05
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author Hui GE
Zhenghua JIANG
Qian HUANG
Muyun ZHU
Jie YANG
author_facet Hui GE
Zhenghua JIANG
Qian HUANG
Muyun ZHU
Jie YANG
author_sort Hui GE
collection DOAJ
description Background and objective To those patients with advanced lung cancer, the ultimate objective is to improve the curative effect and quality of life, lung function indexes are an important factor. We investigate the change of lung function and the relationship between pulmonary function indexs and survival time in patients with advanced lung cancer. Methods Lung function was detected in 59 cases with lung cancer and 63 normal controls. The relationship between pulmonary function indexs and survival time was analyzed. Results There was significant difference in ventilation function and diffusing capacity between in lung cancer group and control group. Vital capacity (VC), forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), peak expiratory flow% (PEF%), maximal ventilatory volume (MVV) were positively correlated with survival time in patients with advanced lung cancer (r=0.29, 0.28, 0.28, 0.27, 0.26, 0.28, P<0.05), residual volume/total lung capacity was negatively correlated with survival time (r=-0.31, P<0.05). Conclusion The lung function decreases in the patients with lung cancer. VC, FEV1, FVC, PEF, PEF%, MVV, residual volume/total lung capacity were correlated with survival time in patients with advanced lung cancer. The pulmonary function indexs were important marker of prognosis in patients with lung cancer.
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spelling doaj.art-211da450f61a453c8498950ef1dfa6952022-12-21T22:50:17ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872013-07-0116735936310.3779/j.issn.1009-3419.2013.07.05Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung CancerHui GEZhenghua JIANGQian HUANGMuyun ZHUJie YANGBackground and objective To those patients with advanced lung cancer, the ultimate objective is to improve the curative effect and quality of life, lung function indexes are an important factor. We investigate the change of lung function and the relationship between pulmonary function indexs and survival time in patients with advanced lung cancer. Methods Lung function was detected in 59 cases with lung cancer and 63 normal controls. The relationship between pulmonary function indexs and survival time was analyzed. Results There was significant difference in ventilation function and diffusing capacity between in lung cancer group and control group. Vital capacity (VC), forced expiratory volume in one second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF), peak expiratory flow% (PEF%), maximal ventilatory volume (MVV) were positively correlated with survival time in patients with advanced lung cancer (r=0.29, 0.28, 0.28, 0.27, 0.26, 0.28, P<0.05), residual volume/total lung capacity was negatively correlated with survival time (r=-0.31, P<0.05). Conclusion The lung function decreases in the patients with lung cancer. VC, FEV1, FVC, PEF, PEF%, MVV, residual volume/total lung capacity were correlated with survival time in patients with advanced lung cancer. The pulmonary function indexs were important marker of prognosis in patients with lung cancer.http://dx.doi.org/10.3779/j.issn.1009-3419.2013.07.05Lung neoplasmsLung functionSurvival time
spellingShingle Hui GE
Zhenghua JIANG
Qian HUANG
Muyun ZHU
Jie YANG
Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
Chinese Journal of Lung Cancer
Lung neoplasms
Lung function
Survival time
title Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
title_full Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
title_fullStr Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
title_full_unstemmed Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
title_short Correlation between Pulmonary Function Indexes and Survival Time 
in Patients with Advanced Lung Cancer
title_sort correlation between pulmonary function indexes and survival time 
in patients with advanced lung cancer
topic Lung neoplasms
Lung function
Survival time
url http://dx.doi.org/10.3779/j.issn.1009-3419.2013.07.05
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