LRRK2 Regulates CPT1A to Promote β-Oxidation in HepG2 Cells

Leucine-rich repeat kinase 2 (LRRK2) is involved in lipid metabolism; however, the role of LRRK2 in lipid metabolism to affect non-alcoholic fatty liver disease (NAFLD) is still unclear. In the mouse model of NAFLD induced by a high-fat diet, we observed that LRRK2 was decreased in livers. In HepG2...

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Bibliographic Details
Main Authors: Chiao-Wei Lin, Yu-Ju Peng, Yuan-Yu Lin, Harry John Mersmann, Shih-Torng Ding
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/18/4122

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