Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor
Abstract Transfusion‐Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life‐threatening TRALI in an obstetric patient triggered by transfusion from a non‐transfused male blood donor. A residual risk of TRALI ex...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.3818 |
| _version_ | 1818904913096212480 |
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| author | Charlotte Nielsen Agergaard Thure Mors Haunstrup Anne‐Louise Fjordside John Baech Rudi Steffensen Kaspar René Nielsen |
| author_facet | Charlotte Nielsen Agergaard Thure Mors Haunstrup Anne‐Louise Fjordside John Baech Rudi Steffensen Kaspar René Nielsen |
| author_sort | Charlotte Nielsen Agergaard |
| collection | DOAJ |
| description | Abstract Transfusion‐Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life‐threatening TRALI in an obstetric patient triggered by transfusion from a non‐transfused male blood donor. A residual risk of TRALI exist, even in a male‐only plasma setting. |
| first_indexed | 2024-12-19T21:14:59Z |
| format | Article |
| id | doaj.art-2120429e17cd4e448b79e1fb172064c8 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-19T21:14:59Z |
| publishDate | 2021-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-2120429e17cd4e448b79e1fb172064c82022-12-21T20:05:22ZengWileyClinical Case Reports2050-09042021-06-0196n/an/a10.1002/ccr3.3818Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donorCharlotte Nielsen Agergaard0Thure Mors Haunstrup1Anne‐Louise Fjordside2John Baech3Rudi Steffensen4Kaspar René Nielsen5Department of Clinical Immunology Odense University Hospital Odense DenmarkDepartment of Clinical Immunology Aalborg University Hospital Aalborg DenmarkDepartment of Clinical Immunology Aalborg University Hospital Aalborg DenmarkDepartment of Clinical Immunology Aalborg University Hospital Aalborg DenmarkDepartment of Clinical Immunology Aalborg University Hospital Aalborg DenmarkDepartment of Clinical Immunology Aalborg University Hospital Aalborg DenmarkAbstract Transfusion‐Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life‐threatening TRALI in an obstetric patient triggered by transfusion from a non‐transfused male blood donor. A residual risk of TRALI exist, even in a male‐only plasma setting.https://doi.org/10.1002/ccr3.3818neutrophil antibodiesplasmaTRALITransfusion |
| spellingShingle | Charlotte Nielsen Agergaard Thure Mors Haunstrup Anne‐Louise Fjordside John Baech Rudi Steffensen Kaspar René Nielsen Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor Clinical Case Reports neutrophil antibodies plasma TRALI Transfusion |
| title | Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor |
| title_full | Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor |
| title_fullStr | Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor |
| title_full_unstemmed | Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor |
| title_short | Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor |
| title_sort | severe antibody mediated transfusion related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non transfused male blood donor |
| topic | neutrophil antibodies plasma TRALI Transfusion |
| url | https://doi.org/10.1002/ccr3.3818 |
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