A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B
Background: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/21/6901 |
| _version_ | 1797631704025792512 |
|---|---|
| author | Sylwia Czajkowska Joanna Rupa-Matysek Kacper Nijakowski Lidia Gil Anna Surdacka Tomasz Kulczyk |
| author_facet | Sylwia Czajkowska Joanna Rupa-Matysek Kacper Nijakowski Lidia Gil Anna Surdacka Tomasz Kulczyk |
| author_sort | Sylwia Czajkowska |
| collection | DOAJ |
| description | Background: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index (KI)) to assess the risk of reduced bone mineral density (BMD) in patients with hemophilia A/B. Methods: The study group consisted of 50 patients with type A/B hemophilia. The control group consisted of 25 males without congenital bleeding disorders. The patients had a panoramic radiograph taken with the same X-ray machine (Vistapano S, Durr Dental, Bietigheim-Bissingen, Germany). The AudaXCeph software (Audax d.o.o., Ljubljana, Slovenia) was used to evaluate the AI index, and the ImageJ, software with a specially prepared script, was used to evaluate the FD. The mandibular cortex was assessed distal to the mental foramen using the Klemetti index. Results: There were no statistically significant differences between the AI, KI and FD values between the study group and the control group. Conclusions: This study indicated the lack of usefulness of AI, KI and fractal analysis in identifying patients with hemophilia at risk of reduced bone mass. |
| first_indexed | 2024-03-11T11:26:00Z |
| format | Article |
| id | doaj.art-212456abd8994ea5a6b189d81f2bb80d |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T11:26:00Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-212456abd8994ea5a6b189d81f2bb80d2023-11-10T15:06:51ZengMDPI AGJournal of Clinical Medicine2077-03832023-11-011221690110.3390/jcm12216901A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and BSylwia Czajkowska0Joanna Rupa-Matysek1Kacper Nijakowski2Lidia Gil3Anna Surdacka4Tomasz Kulczyk5Department of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, PolandDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-812 Poznan, PolandDepartment of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, PolandDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, 60-812 Poznan, PolandDepartment of Conservative Dentistry and Endodontics, Poznan University of Medical Sciences, 60-812 Poznan, PolandDepartment of Diagnostics, Poznan University of Medical Sciences, 60-812 Poznan, PolandBackground: Hemophilia is associated with an increased risk of developing osteoporosis and osteopenia. The aim of the study was to interpret the usefulness of fractal analysis of the trabecular bone of the mandible (FD) and selected radiomorphic indices (the antegonial index (AI) and Klemetti index (KI)) to assess the risk of reduced bone mineral density (BMD) in patients with hemophilia A/B. Methods: The study group consisted of 50 patients with type A/B hemophilia. The control group consisted of 25 males without congenital bleeding disorders. The patients had a panoramic radiograph taken with the same X-ray machine (Vistapano S, Durr Dental, Bietigheim-Bissingen, Germany). The AudaXCeph software (Audax d.o.o., Ljubljana, Slovenia) was used to evaluate the AI index, and the ImageJ, software with a specially prepared script, was used to evaluate the FD. The mandibular cortex was assessed distal to the mental foramen using the Klemetti index. Results: There were no statistically significant differences between the AI, KI and FD values between the study group and the control group. Conclusions: This study indicated the lack of usefulness of AI, KI and fractal analysis in identifying patients with hemophilia at risk of reduced bone mass.https://www.mdpi.com/2077-0383/12/21/6901hemophilia Ahemophilia BradiographypanoramicosteoporosisX-rays |
| spellingShingle | Sylwia Czajkowska Joanna Rupa-Matysek Kacper Nijakowski Lidia Gil Anna Surdacka Tomasz Kulczyk A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B Journal of Clinical Medicine hemophilia A hemophilia B radiography panoramic osteoporosis X-rays |
| title | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
| title_full | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
| title_fullStr | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
| title_full_unstemmed | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
| title_short | A Panoramic X-ray as a Supportive Diagnostic Tool for the Screening of Osteoporosis in Patients with Hemophilia A and B |
| title_sort | panoramic x ray as a supportive diagnostic tool for the screening of osteoporosis in patients with hemophilia a and b |
| topic | hemophilia A hemophilia B radiography panoramic osteoporosis X-rays |
| url | https://www.mdpi.com/2077-0383/12/21/6901 |
| work_keys_str_mv | AT sylwiaczajkowska apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT joannarupamatysek apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT kacpernijakowski apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT lidiagil apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT annasurdacka apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT tomaszkulczyk apanoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT sylwiaczajkowska panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT joannarupamatysek panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT kacpernijakowski panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT lidiagil panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT annasurdacka panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb AT tomaszkulczyk panoramicxrayasasupportivediagnostictoolforthescreeningofosteoporosisinpatientswithhemophiliaaandb |