Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report

<p>Abstract</p> <p>Synchronous composite tumors have been described but are uncommon. Moreover, simultaneous occurrence of synchronous tumors in the same tissue or organ is even less common. We report a case of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma and malig...

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Main Authors: Sur Monalisa, Ross Catherine, El Demellawy Dina, Alowami Salem
Format: Article
Language:English
Published: BMC 2007-08-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/2/1/34
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author Sur Monalisa
Ross Catherine
El Demellawy Dina
Alowami Salem
author_facet Sur Monalisa
Ross Catherine
El Demellawy Dina
Alowami Salem
author_sort Sur Monalisa
collection DOAJ
description <p>Abstract</p> <p>Synchronous composite tumors have been described but are uncommon. Moreover, simultaneous occurrence of synchronous tumors in the same tissue or organ is even less common. We report a case of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma and malignant melanoma (MM) occurring synchronously in the same lymph node. Several cases of an association between cutaneous malignancies and lymphoproliferative disorders have been reported. Some of which included CLL and MM, occurring in the same patient often CLL after MM. The risk of having CLL after MM has been reported to be increased. Various genetic and environmental etiologies have been postulated, but have as yet not been proven. To our knowledge this is the first time that synchronous occurrence of these two malignant processes in the same tissue is described. In this case it is important that the melanoma was recognized in the excised lymph node, as this finding had much more critical treatment and long term survival consequences.</p>
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spelling doaj.art-212532547d644306b5439c8808ccf1c92022-12-21T20:56:31ZengBMCDiagnostic Pathology1746-15962007-08-01213410.1186/1746-1596-2-34Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case reportSur MonalisaRoss CatherineEl Demellawy DinaAlowami Salem<p>Abstract</p> <p>Synchronous composite tumors have been described but are uncommon. Moreover, simultaneous occurrence of synchronous tumors in the same tissue or organ is even less common. We report a case of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma and malignant melanoma (MM) occurring synchronously in the same lymph node. Several cases of an association between cutaneous malignancies and lymphoproliferative disorders have been reported. Some of which included CLL and MM, occurring in the same patient often CLL after MM. The risk of having CLL after MM has been reported to be increased. Various genetic and environmental etiologies have been postulated, but have as yet not been proven. To our knowledge this is the first time that synchronous occurrence of these two malignant processes in the same tissue is described. In this case it is important that the melanoma was recognized in the excised lymph node, as this finding had much more critical treatment and long term survival consequences.</p>http://www.diagnosticpathology.org/content/2/1/34
spellingShingle Sur Monalisa
Ross Catherine
El Demellawy Dina
Alowami Salem
Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
Diagnostic Pathology
title Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
title_full Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
title_fullStr Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
title_full_unstemmed Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
title_short Synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia/small lymphocytic lymphoma: case report
title_sort synchronously diagnosed lymph nodal collision tumor of malignant melanoma and chonic lymphocytic leukemia small lymphocytic lymphoma case report
url http://www.diagnosticpathology.org/content/2/1/34
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AT rosscatherine synchronouslydiagnosedlymphnodalcollisiontumorofmalignantmelanomaandchoniclymphocyticleukemiasmalllymphocyticlymphomacasereport
AT eldemellawydina synchronouslydiagnosedlymphnodalcollisiontumorofmalignantmelanomaandchoniclymphocyticleukemiasmalllymphocyticlymphomacasereport
AT alowamisalem synchronouslydiagnosedlymphnodalcollisiontumorofmalignantmelanomaandchoniclymphocyticleukemiasmalllymphocyticlymphomacasereport