Investigating Ex Vivo Animal Models to Test the Performance of Intravitreal Liposomal Drug Delivery Systems

Investigating Ex Vivo Animal Models to Test the Performance of Intravitreal Liposomal Drug Delivery Systems

There is a strong need for innovative and efficient drug delivery systems for ocular therapy development. However, testing intravitreal drug delivery systems without using live animals is challenging. Ex vivo animal models offer an interesting alternative. We analyzed the potential of using fresh po...

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Bibliographic Details
Main Authors: Gustav Christensen, Leon Barut, Dileep Urimi, Nicolaas Schipper, François Paquet-Durand
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceutics
Subjects:
liposomes
intravitreal
ocular drug delivery
retinal explants
Online Access:https://www.mdpi.com/1999-4923/13/7/1013

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