The Antitumor Activities of Marsdenia tenacissima
Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activat...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-10-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2018.00473/full |
| _version_ | 1818315991922245632 |
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| author | Xiang Wang Xiang Wang Yuanliang Yan Yuanliang Yan Xi Chen Xi Chen Shuangshuang Zeng Shuangshuang Zeng Long Qian Long Qian Xinxin Ren Jie Wei Jie Wei Xue Yang Xue Yang Yangying Zhou Zhicheng Gong Zhicheng Gong Zhijie Xu |
| author_facet | Xiang Wang Xiang Wang Yuanliang Yan Yuanliang Yan Xi Chen Xi Chen Shuangshuang Zeng Shuangshuang Zeng Long Qian Long Qian Xinxin Ren Jie Wei Jie Wei Xue Yang Xue Yang Yangying Zhou Zhicheng Gong Zhicheng Gong Zhijie Xu |
| author_sort | Xiang Wang |
| collection | DOAJ |
| description | Marsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization. |
| first_indexed | 2024-12-13T09:14:20Z |
| format | Article |
| id | doaj.art-212a8a7ac7284ec48588acd9678c787a |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-13T09:14:20Z |
| publishDate | 2018-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-212a8a7ac7284ec48588acd9678c787a2022-12-21T23:52:52ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2018-10-01810.3389/fonc.2018.00473425323The Antitumor Activities of Marsdenia tenacissimaXiang Wang0Xiang Wang1Yuanliang Yan2Yuanliang Yan3Xi Chen4Xi Chen5Shuangshuang Zeng6Shuangshuang Zeng7Long Qian8Long Qian9Xinxin Ren10Jie Wei11Jie Wei12Xue Yang13Xue Yang14Yangying Zhou15Zhicheng Gong16Zhicheng Gong17Zhijie Xu18Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Molecular Radiation Oncology of Hunan Province, Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, ChinaMarsdenia tenacissima (MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization.https://www.frontiersin.org/article/10.3389/fonc.2018.00473/fullMarsdenia tenacissimaantitumor activitiesmalignant tumorsignaling pathwaysefficacytoxicity |
| spellingShingle | Xiang Wang Xiang Wang Yuanliang Yan Yuanliang Yan Xi Chen Xi Chen Shuangshuang Zeng Shuangshuang Zeng Long Qian Long Qian Xinxin Ren Jie Wei Jie Wei Xue Yang Xue Yang Yangying Zhou Zhicheng Gong Zhicheng Gong Zhijie Xu The Antitumor Activities of Marsdenia tenacissima Frontiers in Oncology Marsdenia tenacissima antitumor activities malignant tumor signaling pathways efficacy toxicity |
| title | The Antitumor Activities of Marsdenia tenacissima |
| title_full | The Antitumor Activities of Marsdenia tenacissima |
| title_fullStr | The Antitumor Activities of Marsdenia tenacissima |
| title_full_unstemmed | The Antitumor Activities of Marsdenia tenacissima |
| title_short | The Antitumor Activities of Marsdenia tenacissima |
| title_sort | antitumor activities of marsdenia tenacissima |
| topic | Marsdenia tenacissima antitumor activities malignant tumor signaling pathways efficacy toxicity |
| url | https://www.frontiersin.org/article/10.3389/fonc.2018.00473/full |
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