STAT3: Versatile Functions in Non-Small Cell Lung Cancer

STAT3: Versatile Functions in Non-Small Cell Lung Cancer

Signal Transducer and Activator of Transcription 3 (STAT3) activation is frequently found in non-small cell lung cancer (NSCLC) patient samples/cell lines and STAT3 inhibition in NSCLC cell lines markedly impairs their survival. STAT3 also plays a pivotal role in driving tumor-promoting inflammation...

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Bibliographic Details
Main Authors: Julian Mohrherr, Iris Z. Uras, Herwig P. Moll, Emilio Casanova
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
signal transducer and activator of transcription (STAT)
Janus kinase (JAK)
cytokines
interleukin (IL)
non-small cell lung cancer (NSCLC)
lung adenocarcinoma (AC)
Online Access:https://www.mdpi.com/2072-6694/12/5/1107

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