Additive Behavioral Improvement after Combined Cell Therapy and Rehabilitation Despite Long-Term Microglia Presence in Stroke Rats

Additive Behavioral Improvement after Combined Cell Therapy and Rehabilitation Despite Long-Term Microglia Presence in Stroke Rats

Microglia are involved in the post-stroke immunomodulation of brain plasticity, repair, and reorganization. Here, we evaluated whether adipose-tissue-derived mesenchymal stem cells (ADMSCs) and/or rehabilitation improve behavioral recovery by modulating long-term perilesional inflammation and creati...

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Bibliographic Details
Main Authors: Abdulhameed Bakreen, Miia Juntunen, Yannick Dunlop, Irene F. Ugidos, Tarja Malm, Susanna Miettinen, Jukka Jolkkonen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
stroke
microglia
inflammation
blood–brain barrier
repair
reorganization
Online Access:https://www.mdpi.com/1422-0067/22/4/1512

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