Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature

S Lochy,1 R Jacobs,1 PM Honoré,1 E De Waele,1 O Joannes-Boyau,2 J De Regt,1 V Van Gorp,1 HD Spapen1 1Intensive Care Dept, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium; 2Haut Leveque University Hospital of Bordeaux, University of Bordeaux 2, Pessac, Fr...

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Main Authors: Lochy S, Jacobs R, Honoré PM, De Waele E, Joannes-Boyau O, De Regt J, Van Gorp V, Spapen HD
Format: Article
Language:English
Published: Dove Medical Press 2013-03-01
Series:International Journal of Nephrology and Renovascular Disease
Online Access:http://www.dovepress.com/phosphate-induced-crystal-acute-kidney-injury-ndash-an-under-recognize-a12491
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author Lochy S
Jacobs R
Honoré PM
De Waele E
Joannes-Boyau O
De Regt J
Van Gorp V
Spapen HD
author_facet Lochy S
Jacobs R
Honoré PM
De Waele E
Joannes-Boyau O
De Regt J
Van Gorp V
Spapen HD
author_sort Lochy S
collection DOAJ
description S Lochy,1 R Jacobs,1 PM Honoré,1 E De Waele,1 O Joannes-Boyau,2 J De Regt,1 V Van Gorp,1 HD Spapen1 1Intensive Care Dept, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium; 2Haut Leveque University Hospital of Bordeaux, University of Bordeaux 2, Pessac, France Abstract: Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition – crystal nephropathy – and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administration of a combination of oral and rectal sodium phosphate for treatment of postoperative constipation. A timely renal replacement therapy procedure may reverse the process of crystallization and the irreversible slope towards chronic dialysis. Keywords: hemofiltration, acute phosphate nephropathy, hyperphosphatemie, crystal induced nephropathy, CRRT, worse prognosis, dialysis
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spelling doaj.art-2136953620ab4e18920fc3181bbfeb9b2022-12-22T00:32:43ZengDove Medical PressInternational Journal of Nephrology and Renovascular Disease1178-70582013-03-012013default6164Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literatureLochy SJacobs RHonoré PMDe Waele EJoannes-Boyau ODe Regt JVan Gorp VSpapen HDS Lochy,1 R Jacobs,1 PM Honoré,1 E De Waele,1 O Joannes-Boyau,2 J De Regt,1 V Van Gorp,1 HD Spapen1 1Intensive Care Dept, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium; 2Haut Leveque University Hospital of Bordeaux, University of Bordeaux 2, Pessac, France Abstract: Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition – crystal nephropathy – and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administration of a combination of oral and rectal sodium phosphate for treatment of postoperative constipation. A timely renal replacement therapy procedure may reverse the process of crystallization and the irreversible slope towards chronic dialysis. Keywords: hemofiltration, acute phosphate nephropathy, hyperphosphatemie, crystal induced nephropathy, CRRT, worse prognosis, dialysishttp://www.dovepress.com/phosphate-induced-crystal-acute-kidney-injury-ndash-an-under-recognize-a12491
spellingShingle Lochy S
Jacobs R
Honoré PM
De Waele E
Joannes-Boyau O
De Regt J
Van Gorp V
Spapen HD
Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
International Journal of Nephrology and Renovascular Disease
title Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
title_full Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
title_fullStr Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
title_full_unstemmed Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
title_short Phosphate induced crystal acute kidney injury – an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature
title_sort phosphate induced crystal acute kidney injury amp ndash an under recognized cause of acute kidney injury potentially leading to chronic kidney disease case report and review of the literature
url http://www.dovepress.com/phosphate-induced-crystal-acute-kidney-injury-ndash-an-under-recognize-a12491
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