Relationship between thyroid disorder and iron deficiency anaemia in pregnancy
Background: Thyroid disorders and iron deficiency (ID) are associated with obstetrical and fetal complications. Iron is essential for the normal functioning of thyroid peroxidase (TPO-abs) and ID is frequent during pregnancy. Objective: The present study was undertaken to see the relationship betwee...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Barpeta Obstetrics and Gynaecological Society
2021-01-01
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| Series: | New Indian Journal of OBGYN |
| Subjects: | |
| Online Access: | https://journal.barpetaogs.co.in/pdf/07163.pdf |
| _version_ | 1818557206437560320 |
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| author | Mili D. Chowdhury S.S. Ghose Abhish Mohan |
| author_facet | Mili D. Chowdhury S.S. Ghose Abhish Mohan |
| author_sort | Mili D. Chowdhury |
| collection | DOAJ |
| description | Background: Thyroid disorders and iron deficiency (ID) are associated with obstetrical and fetal complications. Iron is essential for the normal functioning of thyroid peroxidase (TPO-abs) and ID is frequent during pregnancy. Objective: The present study was undertaken to see the relationship between iron deficiency anaemia and thyroid disorder in antenatal cases. Methods: A total of 100 cases attending the outpatient department of Obstetrics and Gynecology in their 1st trimester (from LMP to 12 weeks) were studied at Naval Hospital Powai during a period from Jan 2016 to Dec 2017. A detailed clinical and obstetric history was taken and patients were subjected to routine antenatal investigations along with thyroid profile. Results: Among 100 cases, 21 antenatal cases had increased TSH. Out of which 4 cases had overt hypothyroidism and 17 cases had subclinical hypothyroidism. 2 cases had decreased thyroid stimulating hormone in early trimester out of which only 1 had overt hyperthyroidism. In the same study 23 cases had mild iron deficiency anaemia and 4 had moderate anaemia. It was later correlated that out of 27 cases with anaemia 14 had hypothyroidism. 51% of the cases with anaemia had hypothyroidism and 60% of the hypothyroid cases had iron deficiency anaemia. Applying regression analysis between TSH and Hb level, there was a positive correlation between these two factors in cases. r2 value was found to be 0.2871. This was statistically significant with a P value of less than 0.005. Conclusion: It is concluded that there is increased prevalence of thyroid disorders and iron deficiency anaemia in antenatal cases and there is relationship between iron deficiency anaemia and hypothyroid cases. |
| first_indexed | 2024-12-13T23:56:51Z |
| format | Article |
| id | doaj.art-213753569d404edcb71b3f75824ddd8d |
| institution | Directory Open Access Journal |
| issn | 2454-2334 2454-2342 |
| language | English |
| last_indexed | 2024-12-13T23:56:51Z |
| publishDate | 2021-01-01 |
| publisher | Barpeta Obstetrics and Gynaecological Society |
| record_format | Article |
| series | New Indian Journal of OBGYN |
| spelling | doaj.art-213753569d404edcb71b3f75824ddd8d2022-12-21T23:26:30ZengBarpeta Obstetrics and Gynaecological SocietyNew Indian Journal of OBGYN2454-23342454-23422021-01-017216316710.21276/obgyn.2021.7.2.10Relationship between thyroid disorder and iron deficiency anaemia in pregnancyMili D. Chowdhury0S.S. Ghose1Abhish Mohan2Graded specialist, Department of Obstetrics & Gynaecology, Naval Hospital Powai, Mumbai, Maharashtra, IndiaClassified specialist, Department of Surgery, Naval Hospital Powai, Mumbai, Maharashtra, IndiaGraded specialist, Department of Medicine, Naval Hospital Powai, Mumbai, Maharashtra, IndiaBackground: Thyroid disorders and iron deficiency (ID) are associated with obstetrical and fetal complications. Iron is essential for the normal functioning of thyroid peroxidase (TPO-abs) and ID is frequent during pregnancy. Objective: The present study was undertaken to see the relationship between iron deficiency anaemia and thyroid disorder in antenatal cases. Methods: A total of 100 cases attending the outpatient department of Obstetrics and Gynecology in their 1st trimester (from LMP to 12 weeks) were studied at Naval Hospital Powai during a period from Jan 2016 to Dec 2017. A detailed clinical and obstetric history was taken and patients were subjected to routine antenatal investigations along with thyroid profile. Results: Among 100 cases, 21 antenatal cases had increased TSH. Out of which 4 cases had overt hypothyroidism and 17 cases had subclinical hypothyroidism. 2 cases had decreased thyroid stimulating hormone in early trimester out of which only 1 had overt hyperthyroidism. In the same study 23 cases had mild iron deficiency anaemia and 4 had moderate anaemia. It was later correlated that out of 27 cases with anaemia 14 had hypothyroidism. 51% of the cases with anaemia had hypothyroidism and 60% of the hypothyroid cases had iron deficiency anaemia. Applying regression analysis between TSH and Hb level, there was a positive correlation between these two factors in cases. r2 value was found to be 0.2871. This was statistically significant with a P value of less than 0.005. Conclusion: It is concluded that there is increased prevalence of thyroid disorders and iron deficiency anaemia in antenatal cases and there is relationship between iron deficiency anaemia and hypothyroid cases.https://journal.barpetaogs.co.in/pdf/07163.pdfthyroid disordersironantenatalanaemiahypothyroidism |
| spellingShingle | Mili D. Chowdhury S.S. Ghose Abhish Mohan Relationship between thyroid disorder and iron deficiency anaemia in pregnancy New Indian Journal of OBGYN thyroid disorders iron antenatal anaemia hypothyroidism |
| title | Relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| title_full | Relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| title_fullStr | Relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| title_full_unstemmed | Relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| title_short | Relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| title_sort | relationship between thyroid disorder and iron deficiency anaemia in pregnancy |
| topic | thyroid disorders iron antenatal anaemia hypothyroidism |
| url | https://journal.barpetaogs.co.in/pdf/07163.pdf |
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