Neuropsychiatric Lupus in clinical practice
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50%...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001201021&lng=en&tlng=en |
| _version_ | 1811205870836514816 |
|---|---|
| author | Helena Alessi Lívia Almeida Dutra Pedro Braga Neto José Luiz Pedroso Fabio F. Toso Cristiane Kayser Orlando G. P. Barsottini |
| author_facet | Helena Alessi Lívia Almeida Dutra Pedro Braga Neto José Luiz Pedroso Fabio F. Toso Cristiane Kayser Orlando G. P. Barsottini |
| author_sort | Helena Alessi |
| collection | DOAJ |
| description | ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations. This article reviews major neuropsychiatric manifestations in patients with SLE and discusses their clinical features, radiological findings and treatment options. |
| first_indexed | 2024-04-12T03:38:35Z |
| format | Article |
| id | doaj.art-213798757877457ca65984e03c3c0140 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-12T03:38:35Z |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-213798757877457ca65984e03c3c01402022-12-22T03:49:21ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-422774121021103010.1590/0004-282x20160150S0004-282X2016001201021Neuropsychiatric Lupus in clinical practiceHelena AlessiLívia Almeida DutraPedro Braga NetoJosé Luiz PedrosoFabio F. TosoCristiane KayserOrlando G. P. BarsottiniABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease involving multiple organs, characterized by the production of autoantibodies and the development of tissue injury. The etiology of SLE is partially known, involving multiple genetic and environmental factors. As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. Nineteen neuropsychiatric syndromes have been identified associated with SLE, and can be divided into central and peripheral manifestations. This article reviews major neuropsychiatric manifestations in patients with SLE and discusses their clinical features, radiological findings and treatment options.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001201021&lng=en&tlng=enlúpus eritematoso sistêmicovasculite associada ao lúpus, sistema nervoso centralconvulsõesmielitedoenças autoimunes |
| spellingShingle | Helena Alessi Lívia Almeida Dutra Pedro Braga Neto José Luiz Pedroso Fabio F. Toso Cristiane Kayser Orlando G. P. Barsottini Neuropsychiatric Lupus in clinical practice Arquivos de Neuro-Psiquiatria lúpus eritematoso sistêmico vasculite associada ao lúpus, sistema nervoso central convulsões mielite doenças autoimunes |
| title | Neuropsychiatric Lupus in clinical practice |
| title_full | Neuropsychiatric Lupus in clinical practice |
| title_fullStr | Neuropsychiatric Lupus in clinical practice |
| title_full_unstemmed | Neuropsychiatric Lupus in clinical practice |
| title_short | Neuropsychiatric Lupus in clinical practice |
| title_sort | neuropsychiatric lupus in clinical practice |
| topic | lúpus eritematoso sistêmico vasculite associada ao lúpus, sistema nervoso central convulsões mielite doenças autoimunes |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016001201021&lng=en&tlng=en |
| work_keys_str_mv | AT helenaalessi neuropsychiatriclupusinclinicalpractice AT liviaalmeidadutra neuropsychiatriclupusinclinicalpractice AT pedrobraganeto neuropsychiatriclupusinclinicalpractice AT joseluizpedroso neuropsychiatriclupusinclinicalpractice AT fabioftoso neuropsychiatriclupusinclinicalpractice AT cristianekayser neuropsychiatriclupusinclinicalpractice AT orlandogpbarsottini neuropsychiatriclupusinclinicalpractice |