Optimization of peripheral blood volume for in silico reconstitution of the human B‐cell receptor repertoire

Optimization of peripheral blood volume for in silico reconstitution of the human B‐cell receptor repertoire

B cells recognize antigens via membrane‐expressed B‐cell receptors (BCR) and antibodies. Similar human BCR sequences are frequently found at a significantly higher frequency than that theoretically calculated. Patients infected with SARS‐CoV2 and HIV or with autoimmune diseases share very similar BC...

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Bibliographic Details
Main Authors: Hyunho Lee, Duck Kyun Yoo, Jerome Han, Ki Hyun Kim, Jinsung Noh, Yonghee Lee, Eunjae Lee, Sunghoon Kwon, Junho Chung
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:FEBS Open Bio
Subjects:
antibody
B cell
B cell receptor repertoire
BCR‐based diagnostics
next‐generation sequencing
peripheral blood
Online Access:https://doi.org/10.1002/2211-5463.13467

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