Rational Design of New Monoterpene-Containing Azoles and Their Antifungal Activity

Rational Design of New Monoterpene-Containing Azoles and Their Antifungal Activity

Azole antifungals, including fluconazole, have long been the first-line antifungal agents in the fight against fungal infections. The emergence of drug-resistant strains and the associated increase in mortality from systemic mycoses has prompted the development of new agents based on azoles. We repo...

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Bibliographic Details
Main Authors: Nikolai S. Li-Zhulanov, Nadezhda P. Zaikova, Suat Sari, Dolunay Gülmez, Suna Sabuncuoğlu, Keriman Ozadali-Sari, Sevtap Arikan-Akdagli, Andrey A. Nefedov, Tatyana V. Rybalova, Konstantin P. Volcho, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antibiotics
Subjects:
triazole antifungals
monoterpenoids
hybrids
clinical isolates
CYP51
<i>Candida</i> spp.
Online Access:https://www.mdpi.com/2079-6382/12/5/818

Internet

https://www.mdpi.com/2079-6382/12/5/818

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