A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory

The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum.

Bibliographic Details
Main Authors: Yoav Ben-Simon, Karola Kaefer, Philipp Velicky, Jozsef Csicsvari, Johann G. Danzl, Peter Jonas
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32559-8
Description
Summary:The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum.
ISSN:2041-1723