A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory
The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32559-8 |
| _version_ | 1818517047369269248 |
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| author | Yoav Ben-Simon Karola Kaefer Philipp Velicky Jozsef Csicsvari Johann G. Danzl Peter Jonas |
| author_facet | Yoav Ben-Simon Karola Kaefer Philipp Velicky Jozsef Csicsvari Johann G. Danzl Peter Jonas |
| author_sort | Yoav Ben-Simon |
| collection | DOAJ |
| description | The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum. |
| first_indexed | 2024-12-11T00:50:55Z |
| format | Article |
| id | doaj.art-213b4936ae1145aca1acbf486a8f65d1 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-11T00:50:55Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-213b4936ae1145aca1acbf486a8f65d12022-12-22T01:26:38ZengNature PortfolioNature Communications2041-17232022-08-0113111410.1038/s41467-022-32559-8A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memoryYoav Ben-Simon0Karola Kaefer1Philipp Velicky2Jozsef Csicsvari3Johann G. Danzl4Peter Jonas5Institute of Science and Technology Austria (ISTA)Institute of Science and Technology Austria (ISTA)Institute of Science and Technology Austria (ISTA)Institute of Science and Technology Austria (ISTA)Institute of Science and Technology Austria (ISTA)Institute of Science and Technology Austria (ISTA)The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the CA1, thalamus and claustrum.https://doi.org/10.1038/s41467-022-32559-8 |
| spellingShingle | Yoav Ben-Simon Karola Kaefer Philipp Velicky Jozsef Csicsvari Johann G. Danzl Peter Jonas A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory Nature Communications |
| title | A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| title_full | A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| title_fullStr | A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| title_full_unstemmed | A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| title_short | A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| title_sort | direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory |
| url | https://doi.org/10.1038/s41467-022-32559-8 |
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