CELLULAR RESPONSES TO DNA DAMAGE AND ONCOGENESIS BY THE p53 AND pRb/E2F PATHWAYS

CELLULAR RESPONSES TO DNA DAMAGE AND ONCOGENESIS BY THE p53 AND pRb/E2F PATHWAYS

Cellular responses to stress including DNA damage, show multiple options involving the mechanisms of growth arrest. DNA repair and programmed cell death or apoptosis. Failures in these mechanisms can result in oncogenesis or accelerated senescence. Much of the response is coordinated by p53, a nucle...

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Bibliographic Details
Main Authors: Elza Ibrahim Auerkari, Ismu Suharsono Suwelo, Achmad Tjarta, Santoso Cornain, T. W. Rahardjo, K. Eto, M.A. Ikeda
Format: Article
Language:English
Published: Faculty of Dentistry, Universitas Indonesia 2015-07-01
Series:Journal of Dentistry Indonesia
Subjects:
cellular responses
p53 pathways
pRb/E2F pathways
Online Access:http://jdentistry.ui.ac.id/index.php/JDI/article/view/458

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