miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis

miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis

Pulmonary artery hypertension (PAH) pathology involves extracellular matrix (ECM) remodeling in cardiac tissues, thus promoting cardiac fibrosis progression. miR-29a-3p reportedly inhibits lung progression and liver fibrosis by regulating ECM protein expression; however, its role in PAH-induced fibr...

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Bibliographic Details
Main Authors: Chih-Hsin Hsu, I-Fan Liu, Hsuan-Fu Kuo, Chia-Yang Li, Wei-Shiung Lian, Chia-Yuan Chang, Yung-Hsiang Chen, Wei-Lun Liu, Chi-Yu Lu, Yu-Ru Liu, Tzu-Chieh Lin, Tsung-Ying Lee, Chi-Yuan Huang, Chong-Chao Hsieh, Po-Len Liu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
miR-29a-3p
THBS2
cardiomyocytes
fibrosis
pulmonary arterial hypertension
Online Access:https://www.mdpi.com/1422-0067/22/19/10574

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https://www.mdpi.com/1422-0067/22/19/10574

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