Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health

Abstract Background Who benefits from the commercial biomedical research and development (R&D)? Patients-consumers and investors-shareholders have traditionally been viewed as two distinct groups with conflicting interests: shareholders seek maximum profits, patients - maximum clinical benefit....

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Main Author: Slavek Roller
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Globalization and Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12992-019-0490-x
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author Slavek Roller
author_facet Slavek Roller
author_sort Slavek Roller
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description Abstract Background Who benefits from the commercial biomedical research and development (R&D)? Patients-consumers and investors-shareholders have traditionally been viewed as two distinct groups with conflicting interests: shareholders seek maximum profits, patients - maximum clinical benefit. However, what happens when patients are the shareholders? With billions of dollars of public risk capital channeled into the drug development industry, analysing the complex financial architecture and the market for corporate control is essential for understanding industry’s characteristics, such as pricing strategies or R&D priorities. Results Adding investments by governmentally-mandated retirement schemes, central and promotional banks, and sovereign wealth funds to tax-derived governmental financing shows that the majority of biomedical R&D funding is public in origin. Despite this, even in the high-income countries patients can be denied access to effective treatments due to their high cost. Since these costs are set by the drug development firms that are owned in substantial part by the retirement accounts of said patients, the complex financial architecture of biomedical R&D may be inconsistent with the objectives of the ultimate beneficiaries. Conclusions The divergence in economic and public health performance of the drug development industry is resultant from its financial underwriting by enormously expanded pension schemes, governmentally mandated to represent the interests of “captive” beneficiaries, as well as similar policymaker-designed funding flows, whose standards of transparency, accountability and representation are substantially lower than that of governments themselves. Strengthening those elements of institutional design and thus ensuring active responsible shareholding in the interest of the patients-savers is an under-utilised, but potentially high-impact opportunity for advancing public health.
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spelling doaj.art-21431966542f464cae5616ba97f9b5392022-12-21T23:52:10ZengBMCGlobalization and Health1744-86032019-11-0115111110.1186/s12992-019-0490-xPension and state funds dominating biomedical R&D investment: fiduciary duty and public healthSlavek Roller0Goethe University FrankfurtAbstract Background Who benefits from the commercial biomedical research and development (R&D)? Patients-consumers and investors-shareholders have traditionally been viewed as two distinct groups with conflicting interests: shareholders seek maximum profits, patients - maximum clinical benefit. However, what happens when patients are the shareholders? With billions of dollars of public risk capital channeled into the drug development industry, analysing the complex financial architecture and the market for corporate control is essential for understanding industry’s characteristics, such as pricing strategies or R&D priorities. Results Adding investments by governmentally-mandated retirement schemes, central and promotional banks, and sovereign wealth funds to tax-derived governmental financing shows that the majority of biomedical R&D funding is public in origin. Despite this, even in the high-income countries patients can be denied access to effective treatments due to their high cost. Since these costs are set by the drug development firms that are owned in substantial part by the retirement accounts of said patients, the complex financial architecture of biomedical R&D may be inconsistent with the objectives of the ultimate beneficiaries. Conclusions The divergence in economic and public health performance of the drug development industry is resultant from its financial underwriting by enormously expanded pension schemes, governmentally mandated to represent the interests of “captive” beneficiaries, as well as similar policymaker-designed funding flows, whose standards of transparency, accountability and representation are substantially lower than that of governments themselves. Strengthening those elements of institutional design and thus ensuring active responsible shareholding in the interest of the patients-savers is an under-utilised, but potentially high-impact opportunity for advancing public health.http://link.springer.com/article/10.1186/s12992-019-0490-xPharmaceuticalsDrug developmentAccess to medicinesR&D investmentCorporate governance
spellingShingle Slavek Roller
Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
Globalization and Health
Pharmaceuticals
Drug development
Access to medicines
R&D investment
Corporate governance
title Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
title_full Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
title_fullStr Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
title_full_unstemmed Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
title_short Pension and state funds dominating biomedical R&D investment: fiduciary duty and public health
title_sort pension and state funds dominating biomedical r d investment fiduciary duty and public health
topic Pharmaceuticals
Drug development
Access to medicines
R&D investment
Corporate governance
url http://link.springer.com/article/10.1186/s12992-019-0490-x
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