Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report
ABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are descr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Minas Gerais
2021-12-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351&tlng=en |
| _version_ | 1819282528632045568 |
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| author | M.M. Nunes A.P.V. Garcia K.Y.R. Nakagaki G.D. Cassali |
| author_facet | M.M. Nunes A.P.V. Garcia K.Y.R. Nakagaki G.D. Cassali |
| author_sort | M.M. Nunes |
| collection | DOAJ |
| description | ABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are described. Microscopic evaluation of tumors showed dense cellular neoplastic proliferation, composed of malignant myoepithelial and epithelial cells, formed by varied arrangements and presenting papillary, tubular and solid nest proliferation. Immunohistochemistry was performed for markers Ki67, Cox-2, RE, RP, p63 and HER-2. All cases were positive for p63, confirming the myoepithelial nature of neoplastic cells. The diagnosis of malignant adenomyopithelioma was made possible through the association between histopathological characteristics and immunohistochemical results. |
| first_indexed | 2024-12-24T01:17:01Z |
| format | Article |
| id | doaj.art-21438b2b300843d9bd911d240440af26 |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-12-24T01:17:01Z |
| publishDate | 2021-12-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-21438b2b300843d9bd911d240440af262022-12-21T17:22:44ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622021-12-017361351135610.1590/1678-4162-12312Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case reportM.M. Nuneshttps://orcid.org/0000-0003-0383-3238A.P.V. Garciahttps://orcid.org/0000-0002-0898-6295K.Y.R. Nakagakihttps://orcid.org/0000-0002-0662-9577G.D. Cassalihttps://orcid.org/0000-0002-5650-6743ABSTRACT The malignant adenomyoepithelioma is a rare mammary tumor in women and uncommon in cats with only one report in this species. In this case report, the histopathological and immunohistochemical characteristics of six cases of malignant adenomyopithelioma in the feline mammary gland are described. Microscopic evaluation of tumors showed dense cellular neoplastic proliferation, composed of malignant myoepithelial and epithelial cells, formed by varied arrangements and presenting papillary, tubular and solid nest proliferation. Immunohistochemistry was performed for markers Ki67, Cox-2, RE, RP, p63 and HER-2. All cases were positive for p63, confirming the myoepithelial nature of neoplastic cells. The diagnosis of malignant adenomyopithelioma was made possible through the association between histopathological characteristics and immunohistochemical results.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351&tlng=encatmalignant adenomyoepitheliomadiagnosis |
| spellingShingle | M.M. Nunes A.P.V. Garcia K.Y.R. Nakagaki G.D. Cassali Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report Arquivo Brasileiro de Medicina Veterinária e Zootecnia cat malignant adenomyoepithelioma diagnosis |
| title | Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report |
| title_full | Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report |
| title_fullStr | Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report |
| title_full_unstemmed | Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report |
| title_short | Histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat: case report |
| title_sort | histopathological and immunohistochemical characteristics of malignant adenomyoepithelioma in a cat case report |
| topic | cat malignant adenomyoepithelioma diagnosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701351&tlng=en |
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