Endoplasmic reticulum stress: molecular mechanism and therapeutic targets
Abstract The endoplasmic reticulum (ER) functions as a quality-control organelle for protein homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated degradation, protein chaperons, and autophagy. ER stress is activated when proteostasis is broken with an accumulatio...
| Главные авторы: | , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Nature Publishing Group
2023-09-01
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| Серии: | Signal Transduction and Targeted Therapy |
| Online-ссылка: | https://doi.org/10.1038/s41392-023-01570-w |