Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants
Introduction We hypothesized that nutritional deficiency would be common in a cohort of postpartum, human immunodeficiency virus (HIV)-infected women and their infants. Methods...
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Sociedade Brasileira de Medicina Tropical (SBMT)
2014-12-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000600692&lng=en&tlng=en |
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| author | Jacqueline Pontes Monteiro Maria Letícia Santos Cruz Marisa Márcia Mussi-Pinhata Roberta Garcia Salomão Alceu Jordão Junior Jennifer Suzanne Read José Henrique da Silva Pilotto Rachel Ann Cohen Sonia Karolina Stoszek George Kelly Siberry |
| author_facet | Jacqueline Pontes Monteiro Maria Letícia Santos Cruz Marisa Márcia Mussi-Pinhata Roberta Garcia Salomão Alceu Jordão Junior Jennifer Suzanne Read José Henrique da Silva Pilotto Rachel Ann Cohen Sonia Karolina Stoszek George Kelly Siberry |
| author_sort | Jacqueline Pontes Monteiro |
| collection | DOAJ |
| description | Introduction We hypothesized that nutritional deficiency would be common in a cohort of postpartum, human immunodeficiency virus (HIV)-infected women and their infants. Methods Weight and height, as well as blood concentrations of retinol, α-tocopherol, ferritin, hemoglobin, and zinc, were measured in mothers after delivery and in their infants at birth and at 6-12 weeks and six months of age. Retinol and α-tocopherol levels were quantified by high performance liquid chromatography, and zinc levels were measured by atomic absorption spectrophotometry. The maternal body mass index during pregnancy was adjusted for gestational age (adjBMI). Results Among the 97 women 19.6% were underweight. Laboratory abnormalities were most frequently observed for the hemoglobin (46.4%), zinc (41.1%), retinol (12.5%) and ferritin (6.5%) levels. Five percent of the women had mean corpuscular hemoglobin concentrations < 31g/dL. The most common deficiency in the infants was α-tocopherol (81%) at birth; however, only 18.5% of infants had deficient levels at six months of age. Large percentages of infants had zinc (36.8%) and retinol (29.5%) deficiencies at birth; however, these percentages decreased to 17.5% and 18.5%, respectively, by six months of age. No associations between infant micronutrient deficiencies and either the maternal adjBMI category or maternal micronutrient deficiencies were found. Conclusions Micronutrient deficiencies were common in HIV-infected women and their infants. Micronutrient deficiencies were less prevalent in the infants at six months of age. Neither underweight women nor their infants at birth were at increased risk for micronutrient deficiencies. |
| first_indexed | 2024-04-12T17:31:46Z |
| format | Article |
| id | doaj.art-2146a6fd01ef4ed88889b2fb8e71e4a8 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T17:31:46Z |
| publishDate | 2014-12-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-2146a6fd01ef4ed88889b2fb8e71e4a82022-12-22T03:23:07ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492014-12-0147669270010.1590/0037-8682-0226-2014S0037-86822014000600692Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infantsJacqueline Pontes MonteiroMaria Letícia Santos CruzMarisa Márcia Mussi-PinhataRoberta Garcia SalomãoAlceu Jordão JuniorJennifer Suzanne ReadJosé Henrique da Silva PilottoRachel Ann CohenSonia Karolina StoszekGeorge Kelly SiberryIntroduction We hypothesized that nutritional deficiency would be common in a cohort of postpartum, human immunodeficiency virus (HIV)-infected women and their infants. Methods Weight and height, as well as blood concentrations of retinol, α-tocopherol, ferritin, hemoglobin, and zinc, were measured in mothers after delivery and in their infants at birth and at 6-12 weeks and six months of age. Retinol and α-tocopherol levels were quantified by high performance liquid chromatography, and zinc levels were measured by atomic absorption spectrophotometry. The maternal body mass index during pregnancy was adjusted for gestational age (adjBMI). Results Among the 97 women 19.6% were underweight. Laboratory abnormalities were most frequently observed for the hemoglobin (46.4%), zinc (41.1%), retinol (12.5%) and ferritin (6.5%) levels. Five percent of the women had mean corpuscular hemoglobin concentrations < 31g/dL. The most common deficiency in the infants was α-tocopherol (81%) at birth; however, only 18.5% of infants had deficient levels at six months of age. Large percentages of infants had zinc (36.8%) and retinol (29.5%) deficiencies at birth; however, these percentages decreased to 17.5% and 18.5%, respectively, by six months of age. No associations between infant micronutrient deficiencies and either the maternal adjBMI category or maternal micronutrient deficiencies were found. Conclusions Micronutrient deficiencies were common in HIV-infected women and their infants. Micronutrient deficiencies were less prevalent in the infants at six months of age. Neither underweight women nor their infants at birth were at increased risk for micronutrient deficiencies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000600692&lng=en&tlng=enMicronutrientsHIV infectionPregnancyInfantNutritionCohort |
| spellingShingle | Jacqueline Pontes Monteiro Maria Letícia Santos Cruz Marisa Márcia Mussi-Pinhata Roberta Garcia Salomão Alceu Jordão Junior Jennifer Suzanne Read José Henrique da Silva Pilotto Rachel Ann Cohen Sonia Karolina Stoszek George Kelly Siberry Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants Revista da Sociedade Brasileira de Medicina Tropical Micronutrients HIV infection Pregnancy Infant Nutrition Cohort |
| title | Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants |
| title_full | Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants |
| title_fullStr | Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants |
| title_full_unstemmed | Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants |
| title_short | Vitamin A, vitamin E, iron and zinc status in a cohort of HIV-infected mothers and their uninfected infants |
| title_sort | vitamin a vitamin e iron and zinc status in a cohort of hiv infected mothers and their uninfected infants |
| topic | Micronutrients HIV infection Pregnancy Infant Nutrition Cohort |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000600692&lng=en&tlng=en |
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