Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide
Amyloid β (Aβ) peptide is present as a major component in amyloid plaque that is one of the hallmarks of Alzheimer's disease. The peptide contains a single tyrosine residue and Aβ has a major implication in the pathology of the disease progression. Current investigation revealed that the tyrosi...
Main Authors: | Swagata Das, Supriya Das, Anupam Roy, Uttam Pal, Nakul C. Maiti |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2016-01-01
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Series: | Royal Society Open Science |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.160112 |
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