Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives
Mycetoma is a neglected tropical disease that is associated with poor communities and socioeconomically impaired individuals in the tropical and sub-tropical areas. Interestingly, the disease is caused by either bacteria (actinomycetoma) or fungus (eumycetoma). The latter form of the disease, eumyce...
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| Format: | Article |
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MDPI AG
2021-11-01
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| Series: | Microbiology Research |
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| Online Access: | https://www.mdpi.com/2036-7481/12/4/66 |
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| author | Emmanuel Edwar Siddig Ayman Ahmed Yousif Ali Sahar Mubarak Bakhiet Nouh Saad Mohamed Eiman Siddig Ahmed Ahmed Hassan Fahal |
| author_facet | Emmanuel Edwar Siddig Ayman Ahmed Yousif Ali Sahar Mubarak Bakhiet Nouh Saad Mohamed Eiman Siddig Ahmed Ahmed Hassan Fahal |
| author_sort | Emmanuel Edwar Siddig |
| collection | DOAJ |
| description | Mycetoma is a neglected tropical disease that is associated with poor communities and socioeconomically impaired individuals in the tropical and sub-tropical areas. Interestingly, the disease is caused by either bacteria (actinomycetoma) or fungus (eumycetoma). The latter form of the disease, eumycetoma, is the most common type in Africa. Eumycetoma is characterized by a prolonged disease duration and low cure rate. The effective case management of eumycetoma largely depends on the accurate diagnosis and identification of the causative agent to the species level and evaluating its susceptibility to the available drugs. This review summarizes the currently available and used antifungal agents for the treatment of eumycetoma and discusses optimizing the newly developed antifungals as a potential second line for eumycetoma treatment. |
| first_indexed | 2024-03-10T03:32:58Z |
| format | Article |
| id | doaj.art-2153295366d84e00a6011c3d741c9621 |
| institution | Directory Open Access Journal |
| issn | 2036-7481 |
| language | English |
| last_indexed | 2024-03-10T03:32:58Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microbiology Research |
| spelling | doaj.art-2153295366d84e00a6011c3d741c96212023-11-23T09:35:11ZengMDPI AGMicrobiology Research2036-74812021-11-0112489990610.3390/microbiolres12040066Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and PerspectivesEmmanuel Edwar Siddig0Ayman Ahmed1Yousif Ali2Sahar Mubarak Bakhiet3Nouh Saad Mohamed4Eiman Siddig Ahmed5Ahmed Hassan Fahal6Mycetoma Research Center, University of Khartoum, Khartoum GJ5C+4HM, SudanInstitute of Endemic Disease, University of Khartoum, Khartoum JG5R+WXF, SudanHealth Emergencies and Epidemics Control General Directorate, Sudan Federal Ministry of Health, Khartoum JG6Q+83H, SudanMycetoma Research Center, University of Khartoum, Khartoum GJ5C+4HM, SudanDepartment of Parasitology and Medical Entomology, Faculty of Medical Laboratory Sciences, Nile University, Khartoum HJV8+XM, SudanMycetoma Research Center, University of Khartoum, Khartoum GJ5C+4HM, SudanMycetoma Research Center, University of Khartoum, Khartoum GJ5C+4HM, SudanMycetoma is a neglected tropical disease that is associated with poor communities and socioeconomically impaired individuals in the tropical and sub-tropical areas. Interestingly, the disease is caused by either bacteria (actinomycetoma) or fungus (eumycetoma). The latter form of the disease, eumycetoma, is the most common type in Africa. Eumycetoma is characterized by a prolonged disease duration and low cure rate. The effective case management of eumycetoma largely depends on the accurate diagnosis and identification of the causative agent to the species level and evaluating its susceptibility to the available drugs. This review summarizes the currently available and used antifungal agents for the treatment of eumycetoma and discusses optimizing the newly developed antifungals as a potential second line for eumycetoma treatment.https://www.mdpi.com/2036-7481/12/4/66eumycetomaantifungalin vitro susceptibilityanimal models |
| spellingShingle | Emmanuel Edwar Siddig Ayman Ahmed Yousif Ali Sahar Mubarak Bakhiet Nouh Saad Mohamed Eiman Siddig Ahmed Ahmed Hassan Fahal Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives Microbiology Research eumycetoma antifungal in vitro susceptibility animal models |
| title | Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives |
| title_full | Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives |
| title_fullStr | Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives |
| title_full_unstemmed | Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives |
| title_short | Eumycetoma Medical Treatment: Past, Current Practice, Latest Advances and Perspectives |
| title_sort | eumycetoma medical treatment past current practice latest advances and perspectives |
| topic | eumycetoma antifungal in vitro susceptibility animal models |
| url | https://www.mdpi.com/2036-7481/12/4/66 |
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