Levcromakalim provokes an acute rapid-onset migraine-like phenotype without inducing cortical spreading depolarization

Levcromakalim provokes an acute rapid-onset migraine-like phenotype without inducing cortical spreading depolarization

Abstract Background Migraine headache attacks and accompanying sensory augmentation can be induced by several agents including levcromakalim (LVC), that is also capable of provoking aura-like symptoms in migraineurs. We investigated whether single LVC injection causes acute migraine-like phenotype i...

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Bibliographic Details
Main Authors: Berkay Alpay, Bariscan Cimen, Elif Akaydin, Hayrunnisa Bolay, Yildirim Sara
Format: Article
Language:English
Published: BMC 2023-07-01
Series:The Journal of Headache and Pain
Subjects:
Levcromakalim
Migraine
Aura
Cortical spreading depolarization
Rat model
c-fos
Online Access:https://doi.org/10.1186/s10194-023-01627-9

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