Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?

The management of sexual complications after treatment of localized prostate cancer, such as erectile dysfunction, changes in the length of the penis, pain during sexual intercourse, and lack of orgasm, is still an unsolved problem with an important impact on patients’ quality of life. In this revie...

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Main Authors: Roberto Castellucci, Piergustavo De Francesco, Antonio De Palma, Davide Ciavarella, Simone Ferretti, Michele Marchioni, Luigi Schips
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Uro
Subjects:
Online Access:https://www.mdpi.com/2673-4397/3/1/9
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author Roberto Castellucci
Piergustavo De Francesco
Antonio De Palma
Davide Ciavarella
Simone Ferretti
Michele Marchioni
Luigi Schips
author_facet Roberto Castellucci
Piergustavo De Francesco
Antonio De Palma
Davide Ciavarella
Simone Ferretti
Michele Marchioni
Luigi Schips
author_sort Roberto Castellucci
collection DOAJ
description The management of sexual complications after treatment of localized prostate cancer, such as erectile dysfunction, changes in the length of the penis, pain during sexual intercourse, and lack of orgasm, is still an unsolved problem with an important impact on patients’ quality of life. In this review, we summarize the current scientific literature about the rehabilitation of erectile dysfunction after prostate cancer treatment. The therapy for penile rehabilitation includes different types of treatments: the combination of phosphodiesterase type 5 inhibitors (PDE5-I) and the vacuum erectile device (VED) are considered first-line treatment options. When therapy begins, the duration of treatment, the dosage and the drug used all play very important roles in the treatment outcome. Intracavernous injection (ICI) therapy represents the second-line option for patients ineligible for PDE5-I therapy. Technological development has led to the emergence of devices for the stimulation of the penis without the use of drugs, such as penile vibratory stimulation (PVS) for stimulation of ejaculation in spinal cord injury and low-intensity extracorporeal shockwave therapy (LIESWT). The rapid diffusion of the latter, thanks to its easy use, attains good results without side effects. The panorama of penile rehabilitation after PC treatments is vast and many studies are needed, especially on new technologies, to find the best therapeutic regimen possible, personalized to the patient’s characteristics and the type of treatment for PC.
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spelling doaj.art-21586a3ef5c24814af74441f82e3c5d32023-11-17T14:16:46ZengMDPI AGUro2673-43972023-02-0131617310.3390/uro3010009Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?Roberto Castellucci0Piergustavo De Francesco1Antonio De Palma2Davide Ciavarella3Simone Ferretti4Michele Marchioni5Luigi Schips6Department of Urology, ASL Abruzzo 2, 66100 Chieti, ItalyDepartment of Urology, ASL Abruzzo 2, 66100 Chieti, ItalyUnit of Urology, Department of Medical Oral and Biotechnological Sciences, SS. Annunziata Hospital, G. d’Annunzio University, 66100 Chieti, ItalyUnit of Urology, Department of Medical Oral and Biotechnological Sciences, SS. Annunziata Hospital, G. d’Annunzio University, 66100 Chieti, ItalyUnit of Urology, Department of Medical Oral and Biotechnological Sciences, SS. Annunziata Hospital, G. d’Annunzio University, 66100 Chieti, ItalyDepartment of Urology, ASL Abruzzo 2, 66100 Chieti, ItalyDepartment of Urology, ASL Abruzzo 2, 66100 Chieti, ItalyThe management of sexual complications after treatment of localized prostate cancer, such as erectile dysfunction, changes in the length of the penis, pain during sexual intercourse, and lack of orgasm, is still an unsolved problem with an important impact on patients’ quality of life. In this review, we summarize the current scientific literature about the rehabilitation of erectile dysfunction after prostate cancer treatment. The therapy for penile rehabilitation includes different types of treatments: the combination of phosphodiesterase type 5 inhibitors (PDE5-I) and the vacuum erectile device (VED) are considered first-line treatment options. When therapy begins, the duration of treatment, the dosage and the drug used all play very important roles in the treatment outcome. Intracavernous injection (ICI) therapy represents the second-line option for patients ineligible for PDE5-I therapy. Technological development has led to the emergence of devices for the stimulation of the penis without the use of drugs, such as penile vibratory stimulation (PVS) for stimulation of ejaculation in spinal cord injury and low-intensity extracorporeal shockwave therapy (LIESWT). The rapid diffusion of the latter, thanks to its easy use, attains good results without side effects. The panorama of penile rehabilitation after PC treatments is vast and many studies are needed, especially on new technologies, to find the best therapeutic regimen possible, personalized to the patient’s characteristics and the type of treatment for PC.https://www.mdpi.com/2673-4397/3/1/9prostate cancerprostate cancer treatmentradiotherapycastration therapyradical prostatectomyerectile disfunction
spellingShingle Roberto Castellucci
Piergustavo De Francesco
Antonio De Palma
Davide Ciavarella
Simone Ferretti
Michele Marchioni
Luigi Schips
Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
Uro
prostate cancer
prostate cancer treatment
radiotherapy
castration therapy
radical prostatectomy
erectile disfunction
title Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
title_full Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
title_fullStr Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
title_full_unstemmed Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
title_short Penile Rehabilitation after Prostate Cancer Treatment: Which Is the Right Program?
title_sort penile rehabilitation after prostate cancer treatment which is the right program
topic prostate cancer
prostate cancer treatment
radiotherapy
castration therapy
radical prostatectomy
erectile disfunction
url https://www.mdpi.com/2673-4397/3/1/9
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