Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets
The effects of early supplementation with oat β-glucan during the suckling period on piglet gut microbiota composition, concentrations of short-chain fatty acids, and gut physiological markers were assessed. Fifty piglets from five litters, balanced for sex and birth weight, were divided within litt...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Online Access: | https://www.mdpi.com/2076-2615/13/8/1349 |
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| author | Lidija Arapovic Yi Huang Elin Manell Else Verbeek Linda Keeling Li Sun Rikard Landberg Torbjörn Lundh Jan Erik Lindberg Johan Dicksved |
| author_facet | Lidija Arapovic Yi Huang Elin Manell Else Verbeek Linda Keeling Li Sun Rikard Landberg Torbjörn Lundh Jan Erik Lindberg Johan Dicksved |
| author_sort | Lidija Arapovic |
| collection | DOAJ |
| description | The effects of early supplementation with oat β-glucan during the suckling period on piglet gut microbiota composition, concentrations of short-chain fatty acids, and gut physiological markers were assessed. Fifty piglets from five litters, balanced for sex and birth weight, were divided within litters into two treatment groups: β-glucan and control. Piglets in the β-glucan group received the supplement three times/week from day 7 of age until weaning. Rectal swab samples were collected from 10 piglets per treatment group (balanced across litters) from week 1 to week 4, and plasma samples were collected at 1, 3, and 4 weeks of age. Additional samples of intestinal tissues and jugular and portal vein plasma were collected from 10 animals at weaning (one per treatment group and litter). The concentrations of short-chain fatty acids in plasma and the microbiota composition in rectal swabs were mainly influenced by piglet age, rather than the supplement. There were significant differences in microbiota composition between litters and several correlations between concentrations of short-chain fatty acids in plasma and specific microbial taxa in rectal swabs. Overall, β-glucan supplementation did not have any clear impact on the gut environment in suckling piglets, whereas a clear age-related pattern emerged. |
| first_indexed | 2024-03-11T05:18:37Z |
| format | Article |
| id | doaj.art-215a210ad1e247c29c86735d20e8069d |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T05:18:37Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-215a210ad1e247c29c86735d20e8069d2023-11-17T18:00:33ZengMDPI AGAnimals2076-26152023-04-01138134910.3390/ani13081349Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling PigletsLidija Arapovic0Yi Huang1Elin Manell2Else Verbeek3Linda Keeling4Li Sun5Rikard Landberg6Torbjörn Lundh7Jan Erik Lindberg8Johan Dicksved9Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Environment and Health, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Environment and Health, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Biology and Biological Engineering, Division of Food and Nutrition Science, Chalmers University of Technology, SE-412 96 Gothenburg, SwedenDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenDepartment of Animal Nutrition and Management, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, SwedenThe effects of early supplementation with oat β-glucan during the suckling period on piglet gut microbiota composition, concentrations of short-chain fatty acids, and gut physiological markers were assessed. Fifty piglets from five litters, balanced for sex and birth weight, were divided within litters into two treatment groups: β-glucan and control. Piglets in the β-glucan group received the supplement three times/week from day 7 of age until weaning. Rectal swab samples were collected from 10 piglets per treatment group (balanced across litters) from week 1 to week 4, and plasma samples were collected at 1, 3, and 4 weeks of age. Additional samples of intestinal tissues and jugular and portal vein plasma were collected from 10 animals at weaning (one per treatment group and litter). The concentrations of short-chain fatty acids in plasma and the microbiota composition in rectal swabs were mainly influenced by piglet age, rather than the supplement. There were significant differences in microbiota composition between litters and several correlations between concentrations of short-chain fatty acids in plasma and specific microbial taxa in rectal swabs. Overall, β-glucan supplementation did not have any clear impact on the gut environment in suckling piglets, whereas a clear age-related pattern emerged.https://www.mdpi.com/2076-2615/13/8/1349β-glucanmicrobiotaSCFAsuckling piglets |
| spellingShingle | Lidija Arapovic Yi Huang Elin Manell Else Verbeek Linda Keeling Li Sun Rikard Landberg Torbjörn Lundh Jan Erik Lindberg Johan Dicksved Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets Animals β-glucan microbiota SCFA suckling piglets |
| title | Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets |
| title_full | Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets |
| title_fullStr | Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets |
| title_full_unstemmed | Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets |
| title_short | Age Rather Than Supplementation with Oat β-Glucan Influences Development of the Intestinal Microbiota and SCFA Concentrations in Suckling Piglets |
| title_sort | age rather than supplementation with oat β glucan influences development of the intestinal microbiota and scfa concentrations in suckling piglets |
| topic | β-glucan microbiota SCFA suckling piglets |
| url | https://www.mdpi.com/2076-2615/13/8/1349 |
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