Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect
Objective To establish the preparation technology and production method of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect and to evaluate its efficacy in preliminary clinical application. Methods Four patients with Paprosky ⅡB bone defect of the acetabulum who wer...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Army Medical University
2022-08-01
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| Series: | 陆军军医大学学报 |
| Subjects: | |
| Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202112205.htm |
| _version_ | 1818490680807260160 |
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| author | FAN Huaquan WANG Fuyou HE Rui CHEN Xin YANG Liu |
| author_facet | FAN Huaquan WANG Fuyou HE Rui CHEN Xin YANG Liu |
| author_sort | FAN Huaquan |
| collection | DOAJ |
| description | Objective To establish the preparation technology and production method of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect and to evaluate its efficacy in preliminary clinical application. Methods Four patients with Paprosky ⅡB bone defect of the acetabulum who were going to undergo total hip arthroplasty (THA) in our center from June to December 2018 were recruited in this study according to our inclusion and exclusion criteria. Based on the personalized CT data of the patient's complete pelvis, the prosthesis for acetabular bone defect was designed by specialized 3D software and fabricated by powder bed electron beam additive manufacturing. The hip visual analog scale (VAS) score, 36-item short-form (SF-36) score and Harris score for hip joint before and after operation were compared, the postoperative complications were observed, and radiographical examination was completed at the last follow-up. Results All patients obtained good postoperative outcomes after undergoing computer-designed, personalized 3D printed porous tantalum prosthesis assisted THA to repair Paprosky ⅡB acetabular defects. During a follow-up period of 22.5±3.5 months, no surgery-related complications occurred. At the last follow-up, the Harris score was 86.2±0.3, which was significantly higher than that before operation (64.5±12.1), indicating significantly improved hip function; The VAS score was 2.5±0.7, obviously lower than that before operation (7.5±0.7); the SF-36 score was increased from 39.3±6.3 to 81.6±3.8. Compared to preoperative conditions, significant improvement was achieved in quality of life. Radiological examination showed that the implanted hip prosthesis and the 3D printed porous tantalum prosthesis for the bone defect had good stability, no radiolucent line was observed, and the acetabular bone defect was effectively reconstructed. Conclusion Our established preparation technology of personalized 3D printed porous tantalum prosthesis has demonstrated excellent effectiveness for reconstruction of acetabular bone defects in preliminary clinical application.
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| first_indexed | 2024-12-10T17:20:13Z |
| format | Article |
| id | doaj.art-215ae176d89e47b185b3ae2aafca92d4 |
| institution | Directory Open Access Journal |
| issn | 2097-0927 |
| language | zho |
| last_indexed | 2024-12-10T17:20:13Z |
| publishDate | 2022-08-01 |
| publisher | Editorial Office of Journal of Army Medical University |
| record_format | Article |
| series | 陆军军医大学学报 |
| spelling | doaj.art-215ae176d89e47b185b3ae2aafca92d42022-12-22T01:39:59ZzhoEditorial Office of Journal of Army Medical University陆军军医大学学报2097-09272022-08-0144151516152210.16016/j.2097-0927.202112205Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defectFAN Huaquan0WANG Fuyou1 HE Rui2CHEN Xin3YANG Liu4Center for Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, ChinaCenter for Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, ChinaCenter for Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, ChinaCenter for Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, ChinaCenter for Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, ChinaObjective To establish the preparation technology and production method of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect and to evaluate its efficacy in preliminary clinical application. Methods Four patients with Paprosky ⅡB bone defect of the acetabulum who were going to undergo total hip arthroplasty (THA) in our center from June to December 2018 were recruited in this study according to our inclusion and exclusion criteria. Based on the personalized CT data of the patient's complete pelvis, the prosthesis for acetabular bone defect was designed by specialized 3D software and fabricated by powder bed electron beam additive manufacturing. The hip visual analog scale (VAS) score, 36-item short-form (SF-36) score and Harris score for hip joint before and after operation were compared, the postoperative complications were observed, and radiographical examination was completed at the last follow-up. Results All patients obtained good postoperative outcomes after undergoing computer-designed, personalized 3D printed porous tantalum prosthesis assisted THA to repair Paprosky ⅡB acetabular defects. During a follow-up period of 22.5±3.5 months, no surgery-related complications occurred. At the last follow-up, the Harris score was 86.2±0.3, which was significantly higher than that before operation (64.5±12.1), indicating significantly improved hip function; The VAS score was 2.5±0.7, obviously lower than that before operation (7.5±0.7); the SF-36 score was increased from 39.3±6.3 to 81.6±3.8. Compared to preoperative conditions, significant improvement was achieved in quality of life. Radiological examination showed that the implanted hip prosthesis and the 3D printed porous tantalum prosthesis for the bone defect had good stability, no radiolucent line was observed, and the acetabular bone defect was effectively reconstructed. Conclusion Our established preparation technology of personalized 3D printed porous tantalum prosthesis has demonstrated excellent effectiveness for reconstruction of acetabular bone defects in preliminary clinical application. http://aammt.tmmu.edu.cn/Upload/rhtml/202112205.htm3d printingtantalumbone defecttotal hip arthroplasty |
| spellingShingle | FAN Huaquan WANG Fuyou HE Rui CHEN Xin YANG Liu Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect 陆军军医大学学报 3d printing tantalum bone defect total hip arthroplasty |
| title | Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| title_full | Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| title_fullStr | Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| title_full_unstemmed | Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| title_short | Preparation and preliminary clinical application of 3D printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| title_sort | preparation and preliminary clinical application of 3d printed porous tantalum prosthesis for reconstruction of acetabular bone defect |
| topic | 3d printing tantalum bone defect total hip arthroplasty |
| url | http://aammt.tmmu.edu.cn/Upload/rhtml/202112205.htm |
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