Are Nutraceuticals Beneficial in Chronic Kidney Disease?
Chronic kidney disease (CKD) is a worldwide health problem in which prevalence is constantly rising. The pathophysiology of CKD is complicated and has not been fully resolved. However, elevated oxidative stress is considered to play a vital role in the development of this disease. CKD is also though...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-02-01
|
| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/13/2/231 |
| _version_ | 1827602399769919488 |
|---|---|
| author | Jacek Rysz Beata Franczyk Krzysztof Kujawski Izabela Sacewicz-Hofman Aleksanda Ciałkowska-Rysz Anna Gluba-Brzózka |
| author_facet | Jacek Rysz Beata Franczyk Krzysztof Kujawski Izabela Sacewicz-Hofman Aleksanda Ciałkowska-Rysz Anna Gluba-Brzózka |
| author_sort | Jacek Rysz |
| collection | DOAJ |
| description | Chronic kidney disease (CKD) is a worldwide health problem in which prevalence is constantly rising. The pathophysiology of CKD is complicated and has not been fully resolved. However, elevated oxidative stress is considered to play a vital role in the development of this disease. CKD is also thought to be an inflammatory disorder in which uremic toxins participate in the development of the inflammatory milieu. A healthy, balanced diet supports the maintenance of a good health status as it helps to reduce the risk of the development of chronic diseases, including chronic kidney disease, diabetes mellitus, and hypertension. Numerous studies have demonstrated that functional molecules and nutrients, including fatty acids and fiber as well as nutraceuticals such as curcumin, steviol glycosides, and resveratrol not only exert beneficial effects on pro-inflammatory and anti-inflammatory pathways but also on gut mucosa. Nutraceuticals have attracted great interest recently due to their potential favorable physiological effects on the human body and their safety. This review presents some nutraceuticals in which consumption could exert a beneficial impact on the development and progression of renal disease as well cardiovascular disease. |
| first_indexed | 2024-03-09T05:17:50Z |
| format | Article |
| id | doaj.art-215af1f972094d3cb5f14fe03a0f1b95 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-09T05:17:50Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-215af1f972094d3cb5f14fe03a0f1b952023-12-03T12:43:07ZengMDPI AGPharmaceutics1999-49232021-02-0113223110.3390/pharmaceutics13020231Are Nutraceuticals Beneficial in Chronic Kidney Disease?Jacek Rysz0Beata Franczyk1Krzysztof Kujawski2Izabela Sacewicz-Hofman3Aleksanda Ciałkowska-Rysz4Anna Gluba-Brzózka5Department of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, 90-549 Lodz, PolandDepartment of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, 90-549 Lodz, PolandDepartment of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, 90-549 Lodz, PolandDepartment of Molecular Cell Mechanisms, Medical University of Lodz, 90-549 Lodz, PolandPalliative Medicine Unit, Department of Oncology, Medical University of Lodz, 90-549 Lodz, PolandDepartment of Nephrology, Hypertension and Family Medicine, Medical University of Lodz, 90-549 Lodz, PolandChronic kidney disease (CKD) is a worldwide health problem in which prevalence is constantly rising. The pathophysiology of CKD is complicated and has not been fully resolved. However, elevated oxidative stress is considered to play a vital role in the development of this disease. CKD is also thought to be an inflammatory disorder in which uremic toxins participate in the development of the inflammatory milieu. A healthy, balanced diet supports the maintenance of a good health status as it helps to reduce the risk of the development of chronic diseases, including chronic kidney disease, diabetes mellitus, and hypertension. Numerous studies have demonstrated that functional molecules and nutrients, including fatty acids and fiber as well as nutraceuticals such as curcumin, steviol glycosides, and resveratrol not only exert beneficial effects on pro-inflammatory and anti-inflammatory pathways but also on gut mucosa. Nutraceuticals have attracted great interest recently due to their potential favorable physiological effects on the human body and their safety. This review presents some nutraceuticals in which consumption could exert a beneficial impact on the development and progression of renal disease as well cardiovascular disease.https://www.mdpi.com/1999-4923/13/2/231chronic kidney diseasenutraceuticalresveratrolcurcumin |
| spellingShingle | Jacek Rysz Beata Franczyk Krzysztof Kujawski Izabela Sacewicz-Hofman Aleksanda Ciałkowska-Rysz Anna Gluba-Brzózka Are Nutraceuticals Beneficial in Chronic Kidney Disease? Pharmaceutics chronic kidney disease nutraceutical resveratrol curcumin |
| title | Are Nutraceuticals Beneficial in Chronic Kidney Disease? |
| title_full | Are Nutraceuticals Beneficial in Chronic Kidney Disease? |
| title_fullStr | Are Nutraceuticals Beneficial in Chronic Kidney Disease? |
| title_full_unstemmed | Are Nutraceuticals Beneficial in Chronic Kidney Disease? |
| title_short | Are Nutraceuticals Beneficial in Chronic Kidney Disease? |
| title_sort | are nutraceuticals beneficial in chronic kidney disease |
| topic | chronic kidney disease nutraceutical resveratrol curcumin |
| url | https://www.mdpi.com/1999-4923/13/2/231 |
| work_keys_str_mv | AT jacekrysz arenutraceuticalsbeneficialinchronickidneydisease AT beatafranczyk arenutraceuticalsbeneficialinchronickidneydisease AT krzysztofkujawski arenutraceuticalsbeneficialinchronickidneydisease AT izabelasacewiczhofman arenutraceuticalsbeneficialinchronickidneydisease AT aleksandaciałkowskarysz arenutraceuticalsbeneficialinchronickidneydisease AT annaglubabrzozka arenutraceuticalsbeneficialinchronickidneydisease |