Cases of Mediterranean spotted fever in southeast of Iran

In this study the clinical manifestations, laboratory findings, and management of five patients diagnosed with Mediterranean spotted fever (MSF) from southeast of Iran are presented. All patients but one had recent thick-bite histories which were noticeable as black eschars (tache noire). Patients’...

Full description

Bibliographic Details
Main Authors: Mehrdad Farrokhnia, Zohreh Yousefi Ghalejoogh, Mahdi Rohani, Ahmad Ghasemi, Saber Esmaeili, Ehsan Mostafavi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-05-01
Series:Iranian Journal of Microbiology
Subjects:
Online Access:https://ijm.tums.ac.ir/index.php/ijm/article/view/2349
_version_ 1798027099550777344
author Mehrdad Farrokhnia
Zohreh Yousefi Ghalejoogh
Mahdi Rohani
Ahmad Ghasemi
Saber Esmaeili
Ehsan Mostafavi
author_facet Mehrdad Farrokhnia
Zohreh Yousefi Ghalejoogh
Mahdi Rohani
Ahmad Ghasemi
Saber Esmaeili
Ehsan Mostafavi
author_sort Mehrdad Farrokhnia
collection DOAJ
description In this study the clinical manifestations, laboratory findings, and management of five patients diagnosed with Mediterranean spotted fever (MSF) from southeast of Iran are presented. All patients but one had recent thick-bite histories which were noticeable as black eschars (tache noire). Patients’ samples were tested by real-time PCR and serology (IFA). The disease was confirmed by fourfold rising of IgG antibodies against Rickettsia conorii. This is the first report of MSF cases in Iran.
first_indexed 2024-04-11T18:47:02Z
format Article
id doaj.art-2160d4e6a6e845788bcd94bb2f7e4d60
institution Directory Open Access Journal
issn 2008-3289
2008-4447
language English
last_indexed 2024-04-11T18:47:02Z
publishDate 2020-05-01
publisher Tehran University of Medical Sciences
record_format Article
series Iranian Journal of Microbiology
spelling doaj.art-2160d4e6a6e845788bcd94bb2f7e4d602022-12-22T04:08:42ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472020-05-0112310.18502/ijm.v12i3.3244Cases of Mediterranean spotted fever in southeast of IranMehrdad Farrokhnia0Zohreh Yousefi Ghalejoogh1Mahdi Rohani2Ahmad Ghasemi3Saber Esmaeili4Ehsan Mostafavi5Infectious and Tropical Research Center, Kerman University of Medical Sciences, Kerman, IranDepartment of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, IranDepartment of Microbiology, Pasteur Institute of Iran, Tehran, Iran AND National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, IranDepartment of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran AND National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, IranDepartment of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran AND National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, IranDepartment of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran AND National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, Kabudar Ahang, Hamadan, IranIn this study the clinical manifestations, laboratory findings, and management of five patients diagnosed with Mediterranean spotted fever (MSF) from southeast of Iran are presented. All patients but one had recent thick-bite histories which were noticeable as black eschars (tache noire). Patients’ samples were tested by real-time PCR and serology (IFA). The disease was confirmed by fourfold rising of IgG antibodies against Rickettsia conorii. This is the first report of MSF cases in Iran.https://ijm.tums.ac.ir/index.php/ijm/article/view/2349Mediterranean spotted fever;Rickettsia conorii;Tache noire;Tick-borne disease
spellingShingle Mehrdad Farrokhnia
Zohreh Yousefi Ghalejoogh
Mahdi Rohani
Ahmad Ghasemi
Saber Esmaeili
Ehsan Mostafavi
Cases of Mediterranean spotted fever in southeast of Iran
Iranian Journal of Microbiology
Mediterranean spotted fever;
Rickettsia conorii;
Tache noire;
Tick-borne disease
title Cases of Mediterranean spotted fever in southeast of Iran
title_full Cases of Mediterranean spotted fever in southeast of Iran
title_fullStr Cases of Mediterranean spotted fever in southeast of Iran
title_full_unstemmed Cases of Mediterranean spotted fever in southeast of Iran
title_short Cases of Mediterranean spotted fever in southeast of Iran
title_sort cases of mediterranean spotted fever in southeast of iran
topic Mediterranean spotted fever;
Rickettsia conorii;
Tache noire;
Tick-borne disease
url https://ijm.tums.ac.ir/index.php/ijm/article/view/2349
work_keys_str_mv AT mehrdadfarrokhnia casesofmediterraneanspottedfeverinsoutheastofiran
AT zohrehyousefighalejoogh casesofmediterraneanspottedfeverinsoutheastofiran
AT mahdirohani casesofmediterraneanspottedfeverinsoutheastofiran
AT ahmadghasemi casesofmediterraneanspottedfeverinsoutheastofiran
AT saberesmaeili casesofmediterraneanspottedfeverinsoutheastofiran
AT ehsanmostafavi casesofmediterraneanspottedfeverinsoutheastofiran