Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension
Abstract Background: Resistance training (RT) has been recommended as a non-pharmacological treatment for moderate hypertension. In spite of the important role of exercise intensity on training prescription, there is still no data regarding the effects of RT intensity on severe hypertension (SH)....
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Cardiologia (SBC)
2016-01-01
|
| Series: | Arquivos Brasileiros de Cardiologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005005101&lng=en&tlng=en |
| _version_ | 1818132882826199040 |
|---|---|
| author | Rodrigo Vanerson Passos Neves Michel Kendy Souza Clévia Santos Passos Reury Frank Pereira Bacurau Herbert Gustavo Simoes Jonato Prestes Mirian Aparecida Boim Niels Olsen Saraiva Câmara Maria do Carmo Pinho Franco Milton Rocha Moraes |
| author_facet | Rodrigo Vanerson Passos Neves Michel Kendy Souza Clévia Santos Passos Reury Frank Pereira Bacurau Herbert Gustavo Simoes Jonato Prestes Mirian Aparecida Boim Niels Olsen Saraiva Câmara Maria do Carmo Pinho Franco Milton Rocha Moraes |
| author_sort | Rodrigo Vanerson Passos Neves |
| collection | DOAJ |
| description | Abstract Background: Resistance training (RT) has been recommended as a non-pharmacological treatment for moderate hypertension. In spite of the important role of exercise intensity on training prescription, there is still no data regarding the effects of RT intensity on severe hypertension (SH). Objective: This study examined the effects of two RT protocols (vertical ladder climbing), performed at different overloads of maximal weight carried (MWC), on blood pressure (BP) and muscle strength of spontaneously hypertensive rats (SHR) with SH. Methods: Fifteen male SHR ENT#091;206 ± 10 mmHg of systolic BP (SBP)ENT#093; and five Wistar Kyoto rats (WKY; 119 ± 10 mmHg of SBP) were divided into 4 groups: sedentary (SED-WKY) and SHR (SED-SHR); RT1-SHR training relative to body weight (~40% of MWC); and RT2-SHR training relative to MWC test (~70% of MWC). Systolic BP and heart rate (HR) were measured weekly using the tail-cuff method. The progression of muscle strength was determined once every fifteen days. The RT consisted of 3 weekly sessions on non-consecutive days for 12-weeks. Results: Both RT protocols prevented the increase in SBP (delta - 5 and -7 mmHg, respectively; p > 0.05), whereas SBP of the SED-SHR group increased by 19 mmHg (p < 0.05). There was a decrease in HR only for the RT1 group (p < 0.05). There was a higher increase in strength in the RT2 (140%; p < 0.05) group as compared with RT1 (11%; p > 0.05). Conclusions: Our data indicated that both RT protocols were effective in preventing chronic elevation of SBP in SH. Additionally, a higher RT overload induced a greater increase in muscle strength. |
| first_indexed | 2024-12-11T08:43:54Z |
| format | Article |
| id | doaj.art-21623c7a0d014721b57e6c29712026cb |
| institution | Directory Open Access Journal |
| issn | 1678-4170 |
| language | English |
| last_indexed | 2024-12-11T08:43:54Z |
| publishDate | 2016-01-01 |
| publisher | Sociedade Brasileira de Cardiologia (SBC) |
| record_format | Article |
| series | Arquivos Brasileiros de Cardiologia |
| spelling | doaj.art-21623c7a0d014721b57e6c29712026cb2022-12-22T01:14:10ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702016-01-01010.5935/abc.20160019S0066-782X2016005005101Resistance Training in Spontaneously Hypertensive Rats with Severe HypertensionRodrigo Vanerson Passos NevesMichel Kendy SouzaClévia Santos PassosReury Frank Pereira BacurauHerbert Gustavo SimoesJonato PrestesMirian Aparecida BoimNiels Olsen Saraiva CâmaraMaria do Carmo Pinho FrancoMilton Rocha MoraesAbstract Background: Resistance training (RT) has been recommended as a non-pharmacological treatment for moderate hypertension. In spite of the important role of exercise intensity on training prescription, there is still no data regarding the effects of RT intensity on severe hypertension (SH). Objective: This study examined the effects of two RT protocols (vertical ladder climbing), performed at different overloads of maximal weight carried (MWC), on blood pressure (BP) and muscle strength of spontaneously hypertensive rats (SHR) with SH. Methods: Fifteen male SHR ENT#091;206 ± 10 mmHg of systolic BP (SBP)ENT#093; and five Wistar Kyoto rats (WKY; 119 ± 10 mmHg of SBP) were divided into 4 groups: sedentary (SED-WKY) and SHR (SED-SHR); RT1-SHR training relative to body weight (~40% of MWC); and RT2-SHR training relative to MWC test (~70% of MWC). Systolic BP and heart rate (HR) were measured weekly using the tail-cuff method. The progression of muscle strength was determined once every fifteen days. The RT consisted of 3 weekly sessions on non-consecutive days for 12-weeks. Results: Both RT protocols prevented the increase in SBP (delta - 5 and -7 mmHg, respectively; p > 0.05), whereas SBP of the SED-SHR group increased by 19 mmHg (p < 0.05). There was a decrease in HR only for the RT1 group (p < 0.05). There was a higher increase in strength in the RT2 (140%; p < 0.05) group as compared with RT1 (11%; p > 0.05). Conclusions: Our data indicated that both RT protocols were effective in preventing chronic elevation of SBP in SH. Additionally, a higher RT overload induced a greater increase in muscle strength.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005005101&lng=en&tlng=enPressão ArterialForça MuscularTreinamento ResistidoModelo Animal |
| spellingShingle | Rodrigo Vanerson Passos Neves Michel Kendy Souza Clévia Santos Passos Reury Frank Pereira Bacurau Herbert Gustavo Simoes Jonato Prestes Mirian Aparecida Boim Niels Olsen Saraiva Câmara Maria do Carmo Pinho Franco Milton Rocha Moraes Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension Arquivos Brasileiros de Cardiologia Pressão Arterial Força Muscular Treinamento Resistido Modelo Animal |
| title | Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension |
| title_full | Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension |
| title_fullStr | Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension |
| title_full_unstemmed | Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension |
| title_short | Resistance Training in Spontaneously Hypertensive Rats with Severe Hypertension |
| title_sort | resistance training in spontaneously hypertensive rats with severe hypertension |
| topic | Pressão Arterial Força Muscular Treinamento Resistido Modelo Animal |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2016005005101&lng=en&tlng=en |
| work_keys_str_mv | AT rodrigovanersonpassosneves resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT michelkendysouza resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT cleviasantospassos resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT reuryfrankpereirabacurau resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT herbertgustavosimoes resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT jonatoprestes resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT mirianaparecidaboim resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT nielsolsensaraivacamara resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT mariadocarmopinhofranco resistancetraininginspontaneouslyhypertensiveratswithseverehypertension AT miltonrochamoraes resistancetraininginspontaneouslyhypertensiveratswithseverehypertension |